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Loxhd1 Mutations Cause Mechanotransduction Defects in Cochlear Hair Cells

Sound detection happens in the inner ear via the mechanical deflection of the hair bundle of cochlear hair cells. The hair bundle is an apical specialization consisting of actin-filled membrane protrusions (called stereocilia) connected by tip links (TLs) that transfer the deflection force to gate t...

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Detalles Bibliográficos
Autores principales:	Trouillet, Alix, Miller, Katharine K., George, Shefin Sam, Wang, Pei, Ali, Noor-E-Seher, Ricci, Anthony, Grillet, Nicolas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Society for Neuroscience 2021
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8051682/ https://www.ncbi.nlm.nih.gov/pubmed/33707295 http://dx.doi.org/10.1523/JNEUROSCI.0975-20.2021

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