Elevated angiotensin II induces platelet apoptosis through promoting oxidative stress in an AT1R‐dependent manner during sepsis

Thrombocytopenia is independently related with increased mortality in severe septic patients. Renin‐angiotensin system (RAS) is elevated in septic subjects; accumulating studies show that angiotensin II (Ang II) stimulate the intrinsic apoptosis pathway by promoting reactive oxygen species (ROS) pro...

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Detalles Bibliográficos
Autores principales: Xu, Dun‐Feng, Liu, Yu‐Jian, Mao, Yan‐Fei, Wang, Yan, Xu, Chu‐Fan, Zhu, Xiao‐Yan, Jiang, Lai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8051711/
https://www.ncbi.nlm.nih.gov/pubmed/33624364
http://dx.doi.org/10.1111/jcmm.16382

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8051711/
https://www.ncbi.nlm.nih.gov/pubmed/33624364
http://dx.doi.org/10.1111/jcmm.16382

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