Inhibition of miR‐188‐5p alleviates hepatic fibrosis by significantly reducing the activation and proliferation of HSCs through PTEN/PI3K/AKT pathway

Persistent hepatic damage and chronic inflammation in liver activate the quiescent hepatic stellate cells (HSCs) and cause hepatic fibrosis (HF). Several microRNAs regulate the activation and proliferation of HSCs, thereby playing a critical role in HF progression. Previous studies have reported tha...

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Detalles Bibliográficos
Autores principales: Riaz, Farooq, Chen, Qian, Lu, Kaikai, Osoro, Ezra Kombo, Wu, Litao, Feng, Lina, Zhao, Rong, Yang, Luyun, Zhou, Yimeng, He, Yingli, Zhu, Li, Du, Xiaojuan, Sadiq, Muhammad, Yang, Xudong, Li, Dongmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8051718/
https://www.ncbi.nlm.nih.gov/pubmed/33689215
http://dx.doi.org/10.1111/jcmm.16376

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