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Cancer‐associated fibroblast‐derived exosomal microRNA‐24‐3p enhances colon cancer cell resistance to MTX by down‐regulating CDX2/HEPH axis

MicroRNA‐24‐3p (miR‐24‐3p) has been implicated as a key promoter of chemotherapy resistance in numerous cancers. Meanwhile, cancer‐associated fibroblasts (CAFs) can secret exosomes to transfer miRNAs, which mediate tumour development. However, little is known regarding the molecular mechanism of CAF...

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Detalles Bibliográficos
Autores principales: Zhang, Hong‐Wei, Shi, Yi, Liu, Ji‐Bin, Wang, Hui‐Min, Wang, Pei‐Yao, Wu, Zhi‐Jun, Li, Liu, Gu, Li‐Peng, Cao, Ping‐Sheng, Wang, Gao‐Ren, Ma, Yu‐Shui, Fu, Da
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8051723/
https://www.ncbi.nlm.nih.gov/pubmed/33621425
http://dx.doi.org/10.1111/jcmm.15765

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