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Cancer‐associated fibroblast‐derived exosomal microRNA‐24‐3p enhances colon cancer cell resistance to MTX by down‐regulating CDX2/HEPH axis
MicroRNA‐24‐3p (miR‐24‐3p) has been implicated as a key promoter of chemotherapy resistance in numerous cancers. Meanwhile, cancer‐associated fibroblasts (CAFs) can secret exosomes to transfer miRNAs, which mediate tumour development. However, little is known regarding the molecular mechanism of CAF...
Autores principales: | Zhang, Hong‐Wei, Shi, Yi, Liu, Ji‐Bin, Wang, Hui‐Min, Wang, Pei‐Yao, Wu, Zhi‐Jun, Li, Liu, Gu, Li‐Peng, Cao, Ping‐Sheng, Wang, Gao‐Ren, Ma, Yu‐Shui, Fu, Da |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8051723/ https://www.ncbi.nlm.nih.gov/pubmed/33621425 http://dx.doi.org/10.1111/jcmm.15765 |
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