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The aberrant expression in epithelial cells of the mesenchymal isoform of FGFR2 controls the negative crosstalk between EMT and autophagy

Signalling of the epithelial splicing variant of fibroblast growth factor receptor 2 (FGFR2b) triggers both differentiation and autophagy, while the aberrant expression of the mesenchymal FGFR2c isoform in epithelial cells induces impaired differentiation, inhibition of autophagy as well as the indu...

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Detalles Bibliográficos
Autores principales: Ranieri, Danilo, Nanni, Monica, Guttieri, Luisa, Torrisi, Maria Rosaria, Belleudi, Francesca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8051744/
https://www.ncbi.nlm.nih.gov/pubmed/33609078
http://dx.doi.org/10.1111/jcmm.16309