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Enhanced passive surveillance dengue infection among febrile children: Prevalence, co-infections and associated factors in Cameroon
Dengue virus (DENV) causes a spectrum of diseases ranging from asymptomatic, mild febrile to a life-threatening illness: dengue hemorrhagic fever. The main clinical symptom of dengue is fever, similar to that of malaria. The prevalence of dengue virus infection, alone or in association with other en...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8051767/ https://www.ncbi.nlm.nih.gov/pubmed/33861747 http://dx.doi.org/10.1371/journal.pntd.0009316 |
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author | Nkenfou, Celine Nguefeu Fainguem, Nadine Dongmo-Nguefack, Félicitée Yatchou, Laeticia Grace Kameni, Joel Josephine Kadji Elong, Elise Lobe Samie, Amidou Estrin, William Koki, Paul Ndombo Ndjolo, Alexis |
author_facet | Nkenfou, Celine Nguefeu Fainguem, Nadine Dongmo-Nguefack, Félicitée Yatchou, Laeticia Grace Kameni, Joel Josephine Kadji Elong, Elise Lobe Samie, Amidou Estrin, William Koki, Paul Ndombo Ndjolo, Alexis |
author_sort | Nkenfou, Celine Nguefeu |
collection | PubMed |
description | Dengue virus (DENV) causes a spectrum of diseases ranging from asymptomatic, mild febrile to a life-threatening illness: dengue hemorrhagic fever. The main clinical symptom of dengue is fever, similar to that of malaria. The prevalence of dengue virus infection, alone or in association with other endemic infectious diseases in children in Cameroon is unknown. The aim of this study was to determine the prevalence of dengue, malaria and HIV in children presenting with fever and associated risk factors. Dengue overall prevalence was 20.2%, Malaria cases were 52.7% and HIV cases represented 12.6%. The prevalence of dengue-HIV co-infection was 6.0% and that of Malaria-dengue co-infection was 19.5%. Triple infection prevalence was 4.3%. Dengue virus infection is present in children and HIV-Dengue or Dengue- Malaria co-infections are common. Dengue peak prevalence was between August and October. Sex and age were not associated with dengue and dengue co-infections. However, malaria as well as HIV were significantly associated with dengue (P = 0.001 and 0.028 respectively). The diagnosis of dengue and Malaria should be carried out routinely for better management of fever. |
format | Online Article Text |
id | pubmed-8051767 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-80517672021-04-28 Enhanced passive surveillance dengue infection among febrile children: Prevalence, co-infections and associated factors in Cameroon Nkenfou, Celine Nguefeu Fainguem, Nadine Dongmo-Nguefack, Félicitée Yatchou, Laeticia Grace Kameni, Joel Josephine Kadji Elong, Elise Lobe Samie, Amidou Estrin, William Koki, Paul Ndombo Ndjolo, Alexis PLoS Negl Trop Dis Research Article Dengue virus (DENV) causes a spectrum of diseases ranging from asymptomatic, mild febrile to a life-threatening illness: dengue hemorrhagic fever. The main clinical symptom of dengue is fever, similar to that of malaria. The prevalence of dengue virus infection, alone or in association with other endemic infectious diseases in children in Cameroon is unknown. The aim of this study was to determine the prevalence of dengue, malaria and HIV in children presenting with fever and associated risk factors. Dengue overall prevalence was 20.2%, Malaria cases were 52.7% and HIV cases represented 12.6%. The prevalence of dengue-HIV co-infection was 6.0% and that of Malaria-dengue co-infection was 19.5%. Triple infection prevalence was 4.3%. Dengue virus infection is present in children and HIV-Dengue or Dengue- Malaria co-infections are common. Dengue peak prevalence was between August and October. Sex and age were not associated with dengue and dengue co-infections. However, malaria as well as HIV were significantly associated with dengue (P = 0.001 and 0.028 respectively). The diagnosis of dengue and Malaria should be carried out routinely for better management of fever. Public Library of Science 2021-04-16 /pmc/articles/PMC8051767/ /pubmed/33861747 http://dx.doi.org/10.1371/journal.pntd.0009316 Text en © 2021 Nkenfou et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Research Article Nkenfou, Celine Nguefeu Fainguem, Nadine Dongmo-Nguefack, Félicitée Yatchou, Laeticia Grace Kameni, Joel Josephine Kadji Elong, Elise Lobe Samie, Amidou Estrin, William Koki, Paul Ndombo Ndjolo, Alexis Enhanced passive surveillance dengue infection among febrile children: Prevalence, co-infections and associated factors in Cameroon |
title | Enhanced passive surveillance dengue infection among febrile children: Prevalence, co-infections and associated factors in Cameroon |
title_full | Enhanced passive surveillance dengue infection among febrile children: Prevalence, co-infections and associated factors in Cameroon |
title_fullStr | Enhanced passive surveillance dengue infection among febrile children: Prevalence, co-infections and associated factors in Cameroon |
title_full_unstemmed | Enhanced passive surveillance dengue infection among febrile children: Prevalence, co-infections and associated factors in Cameroon |
title_short | Enhanced passive surveillance dengue infection among febrile children: Prevalence, co-infections and associated factors in Cameroon |
title_sort | enhanced passive surveillance dengue infection among febrile children: prevalence, co-infections and associated factors in cameroon |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8051767/ https://www.ncbi.nlm.nih.gov/pubmed/33861747 http://dx.doi.org/10.1371/journal.pntd.0009316 |
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