CSNK1G2 differently sensitizes tamoxifen-induced decrease in PI3K/AKT/mTOR/S6K and ERK signaling according to the estrogen receptor existence in breast cancer cells

Tamoxifen (TAM) is a selective estrogen receptor modulator used for breast cancer patients. Prolonged use of tamoxifen is not recommended for some patients. In this study, we aimed to identify molecular targets sensitive to TAM using a genome-wide gene deletion library screening of fission yeast het...

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Detalles Bibliográficos
Autores principales: Nguyen Hoang, Anh Thu, Hoe, Kwang-Lae, Lee, Sook-Jeong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8051802/
https://www.ncbi.nlm.nih.gov/pubmed/33861751
http://dx.doi.org/10.1371/journal.pone.0246264

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