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Effect of smoking status and programmed death-ligand 1 expression on the microenvironment and malignant transformation of oral leukoplakia: A retrospective cohort study
Tobacco smoking is associated with an increased risk of oral leukoplakia and head and neck cancer. Although it has recently been reported that the establishment of an immunosuppressive microenvironment in oral potentially malignant disorders may lead to malignant transformation, it is unclear whethe...
Autores principales: | Yagyuu, Takahiro, Funayama, Naoki, Imada, Mitsuhiko, Kirita, Tadaaki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8051817/ https://www.ncbi.nlm.nih.gov/pubmed/33861793 http://dx.doi.org/10.1371/journal.pone.0250359 |
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