Cargando…

Electroacupuncture Alleviates Inflammation of Dry Eye Diseases by Regulating the α7nAChR/NF-κB Signaling Pathway

PURPOSE: We tried to investigate whether electroacupuncture (EA) can reduce inflammation of dry eye disease (DED) by regulating α7nAChR and inhibiting the NF-κB signaling pathway. METHODS: Healthy New Zealand white rabbits were treated with scopolamine hydrobromide (Scop) for 21 consecutive days to...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ding, Ning, Wei, Qingbo, Deng, Weimin, Sun, Xinyi, Zhang, Jie, Gao, Weiping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8052151/ https://www.ncbi.nlm.nih.gov/pubmed/33897942 http://dx.doi.org/10.1155/2021/6673610

Ejemplares similares

Acupuncture Alleviates Corneal Inflammation in New Zealand White Rabbits with Dry Eye Diseases by Regulating α7nAChR and NF-κB Signaling Pathway
por: Ding, Ning, et al.
Publicado: (2022)

Sulfonium Ligands of the α7 nAChR
por: Horenstein, Nicole A., et al.
Publicado: (2021)

The Regulation Effect of α7nAChRs and M1AChRs on Inflammation and Immunity in Sepsis
por: Hu, Song, et al.
Publicado: (2021)

Residues Responsible for the Selectivity of α-Conotoxins for Ac-AChBP or nAChRs
por: Lin, Bo, et al.
Publicado: (2016)

Electroacupuncture ameliorates intestinal inflammation by activating α7nAChR-mediated JAK2/STAT3 signaling pathway in postoperative ileus
por: Yang, Na-Na, et al.
Publicado: (2021)

GTS-21 Promotes α7 nAChR to Alleviate Intestinal Ischemia-Reperfusion-Induced Apoptosis and Inflammation of Enterocytes
por: Wang, Haisong, et al.
Publicado: (2020)

Vagal α7nAChR signaling regulates α7nAChR(+)Sca1(+) cells during lung injury repair
por: Chen, Xiaoyan, et al.
Publicado: (2020)

E-cigarette-Induced Pulmonary Inflammation and Dysregulated Repair are Mediated by nAChR α7 Receptor: Role of nAChR α7 in ACE2 Covid-19 receptor regulation
por: Wang, Qixin, et al.
Publicado: (2020)

Nicotine Increases Macrophage Survival through α7nAChR/NF-κB Pathway in Mycobacterium avium paratuberculosis Infection
por: AlQasrawi, Dania, et al.
Publicado: (2021)

Electroacupuncture Pretreatment Ameliorates Anesthesia and Surgery-Induced Cognitive Dysfunction via Activation of an α7-nAChR Signal in Aged Rats
por: Wang, Zhigang, et al.
Publicado: (2021)

AChBP-targeted α-conotoxin correlates distinct binding orientations with nAChR subtype selectivity
por: Dutertre, Sébastien, et al.
Publicado: (2007)

Electroacupuncture attenuated cerebral ischemic injury and neuroinflammation through α7nAChR-mediated inhibition of NLRP3 inflammasome in stroke rats
por: Jiang, Tao, et al.
Publicado: (2019)

Tumor suppressor menin is required for subunit-specific nAChR α5 transcription and nAChR-dependent presynaptic facilitation in cultured mouse hippocampal neurons
por: Getz, Angela M., et al.
Publicado: (2017)

Activation of α7nAChR Protects Against Gastric Inflammation and Dysmotility in Parkinson’s Disease Rats
por: Zhou, Li, et al.
Publicado: (2021)

Interacting with α7 nAChR is a new mechanism for AChE to enhance the inflammatory response in macrophages
por: Liu, Etta Y.L., et al.
Publicado: (2020)

Regulation of RIC-3 and of nAChR expression
por: Ben-David, Yael, et al.
Publicado: (2016)

α-Conotoxin as Potential to α7-nAChR Recombinant Expressed in Escherichia coli
por: Liu, Yanli, et al.
Publicado: (2020)

Characterization of HA-tagged α9 and α10 nAChRs in the mouse cochlea
por: Vyas, Pankhuri, et al.
Publicado: (2020)

Unique Pharmacological Properties of α-Conotoxin OmIA at α7 nAChRs
por: Ho, Thao N.T., et al.
Publicado: (2021)

Farnesyl Transferase Inhibitor Lonafarnib Enhances α7nAChR Expression Through Inhibiting DNA Methylation of CHRNA7 and Increases α7nAChR Membrane Trafficking
por: Chen, Tingting, et al.
Publicado: (2020)

E-cigarette-induced pulmonary inflammation and dysregulated repair are mediated by nAChR α7 receptor: role of nAChR α7 in SARS-CoV-2 Covid-19 ACE2 receptor regulation
por: Wang, Qixin, et al.
Publicado: (2020)

Semisynthetic Analogues of Toxiferine I and Their Pharmacological Properties at α7 nAChRs, Muscle-Type nAChRs, and the Allosteric Binding Site of Muscarinic M(2) Receptors
por: Zlotos, Darius P., et al.
Publicado: (2014)

Electroacupuncture treatment upregulates α7nAChR and inhibits JAK2/STAT3 in dorsal root ganglion of rat with spared nerve injury
por: Wang, Ying, et al.
Publicado: (2019)

Electroacupuncture Ameliorates Tibial Fracture-Induced Cognitive Dysfunction by Elevating α7nAChR Expression and Suppressing Mast Cell Degranulation in the Hippocampus of Rats
por: Zhou, Yudi, et al.
Publicado: (2022)

Vagus Nerve through α7 nAChR Modulates Lung Infection and Inflammation: Models, Cells, and Signals
por: Wu, Haiya, et al.
Publicado: (2014)

α7nAchR/NMDAR coupling affects NMDAR function and object recognition
por: Li, Shupeng, et al.
Publicado: (2013)

In silico studies of ASEM analogues targeting α7-nAChR and experimental verification
por: Zhou, Yang, et al.
Publicado: (2021)

Structural Elucidation of Ivermectin Binding to α7nAChR and the Induced Channel Desensitization
por: Bondarenko, Vasyl, et al.
Publicado: (2023)

New Insights on Neuronal Nicotinic Acetylcholine Receptors as Targets for Pain and Inflammation: A Focus on α7 nAChRs
por: Bagdas, Deniz, et al.
Publicado: (2018)

Cynandione A Alleviates Neuropathic Pain Through α7-nAChR-Dependent IL-10/β-Endorphin Signaling Complexes
por: Han, Qiao-Qiao, et al.
Publicado: (2021)

Menthol Enhances Nicotine Reward-Related Behavior by Potentiating Nicotine-Induced Changes in nAChR Function, nAChR Upregulation, and DA Neuron Excitability
por: Henderson, Brandon J, et al.
Publicado: (2017)

Electroacupuncture attenuates learning and memory impairment via activation of α7nAChR-mediated anti-inflammatory activity in focal cerebral ischemia/reperfusion injured rats
por: Liu, Jiao, et al.
Publicado: (2017)

Ion permeation through neuronal nAChR ion channel
por: Krüger, Jens, et al.
Publicado: (2010)

Effect of the a7nAChR agonist GTS-21 on inflammation during human endotoxemia
por: Pompe, J, et al.
Publicado: (2009)

Modulatory effects of α7 nAChRs on the immune system and its relevance for CNS disorders
por: Kalkman, Hans O., et al.
Publicado: (2016)

Stimulation of α7-nAChRs coordinates autophagy and apoptosis signaling in experimental knee osteoarthritis
por: Liu, Yuan, et al.
Publicado: (2021)

Regulation of the acetylcholine/α7nAChR anti-inflammatory pathway in COVID-19 patients
por: Courties, Alice, et al.
Publicado: (2021)

The Allosteric Activation of α7 nAChR by α-Conotoxin MrIC Is Modified by Mutations at the Vestibular Site
por: Gulsevin, Alican, et al.
Publicado: (2021)

Mechanisms underlying antidepressant effect of transcutaneous auricular vagus nerve stimulation on CUMS model rats based on hippocampal α7nAchR/NF-κB signal pathway
por: Wang, Jun-ying, et al.
Publicado: (2021)

Vagus nerve stimulation promotes resolution of inflammation by a mechanism that involves Alox15 and requires the α7nAChR subunit
por: Caravaca, April S., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_cchcpled8oeahr0pgucgl62ood