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Computer-Aided Drug Discovery Identifies Alkaloid Inhibitors of Parkinson's Disease Associated Protein, Prolyl Oligopeptidase

Parkinson's disease is a common neurodegenerative disorder marked by the accumulation of the protein alpha synuclein. Studies have indicated the role of prolyl oligopeptidase (POP), a serine protease, in alpha synuclein accumulation. Therefore, POP emerges as an attractive medicinal target. Tra...

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Detalles Bibliográficos
Autores principales:	Kulkarni, Apoorva M., Rampogu, Shailima, Lee, Keun Woo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8052153/ https://www.ncbi.nlm.nih.gov/pubmed/33897801 http://dx.doi.org/10.1155/2021/6687572

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