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AKR1C2 and AKR1C3 expression in adipose tissue: Association with body fat distribution and regulatory variants

BACKGROUND: Changes in androgen dynamics within adipose tissue have been proposed as modulators of body fat accumulation. In this context, AKR1C2 likely plays a significant role by inactivating 5α-dihydrotestosterone. AIM: To characterize AKR1C2 expression patterns across adipose depots and cell pop...

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Detalles Bibliográficos
Autores principales: Ostinelli, Giada, Vijay, Jinchu, Vohl, Marie-Claude, Grundberg, Elin, Tchernof, Andre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: North Holland Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8052191/
https://www.ncbi.nlm.nih.gov/pubmed/33675863
http://dx.doi.org/10.1016/j.mce.2021.111220

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