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ILDR2 stabilization is regulated by its interaction with GRP78
Ildr2 was initially identified as a genetic modifier of diabetes susceptibility in B6.DBA Lep(ob) congenic mice, and was associated with decreased β-cell replication rates, reduced β-cell mass, and persistent mild hypoinsulinemic hyperglycemia. However, the molecular mechanisms of how the ILDR2 prot...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8052334/ https://www.ncbi.nlm.nih.gov/pubmed/33863978 http://dx.doi.org/10.1038/s41598-021-87884-7 |