O-GlcNAcylation enhances sensitivity to RSL3-induced ferroptosis via the YAP/TFRC pathway in liver cancer

Ferroptosis is a form of regulated cell death characterized by iron-dependent accumulation of lipid hydroperoxides to lethal levels. YAP has been reported to play a pivotal role in controlling ferroptotic death, and the expression of YAP is enhanced and stabilized by O-GlcNAcylation. However, whethe...

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Detalles Bibliográficos
Autores principales: Zhu, Guoqing, Murshed, Abduh, Li, Haojie, Ma, Ji, Zhen, Ni, Ding, Miao, Zhu, Jiabei, Mao, Siwei, Tang, Xiaochen, Liu, Li, Sun, Fenyong, Jin, Lei, Pan, Qiuhui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8052337/
https://www.ncbi.nlm.nih.gov/pubmed/33863873
http://dx.doi.org/10.1038/s41420-021-00468-2

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