Lipopolysaccharides induce a RAGE-mediated sensitization of sensory neurons and fluid hypersecretion in the upper airways

Thoracic dorsal root ganglia (tDRG) contribute to fluid secretion in the upper airways. Inflammation potentiates DRG responses, but the mechanisms remain under investigation. The receptor for advanced glycation end-products (RAGE) underlies potentiation of DRG responses in pain pathologies; however,...

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Detalles Bibliográficos
Autores principales: Nair, Manoj, Jagadeeshan, Santosh, Katselis, George, Luan, Xiaojie, Momeni, Zeinab, Henao-Romero, Nicolas, Chumala, Paulos, Tam, Julian S., Yamamoto, Yasuhiko, Ianowski, Juan P., Campanucci, Verónica A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8052339/
https://www.ncbi.nlm.nih.gov/pubmed/33863932
http://dx.doi.org/10.1038/s41598-021-86069-6

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