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Detecting protein and DNA/RNA structures in cryo-EM maps of intermediate resolution using deep learning

An increasing number of density maps of macromolecular structures, including proteins and DNA/RNA complexes, have been determined by cryo-electron microscopy (cryo-EM). Although lately maps at a near-atomic resolution are routinely reported, there are still substantial fractions of maps determined a...

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Detalles Bibliográficos
Autores principales: Wang, Xiao, Alnabati, Eman, Aderinwale, Tunde W., Maddhuri Venkata Subramaniya, Sai Raghavendra, Terashi, Genki, Kihara, Daisuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8052361/
https://www.ncbi.nlm.nih.gov/pubmed/33863902
http://dx.doi.org/10.1038/s41467-021-22577-3