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Discovery of a AHR pelargonidin agonist that counter-regulates Ace2 expression and attenuates ACE2-SARS-CoV-2 interaction

The severe acute respiratory syndrome (SARS)-CoV-2 is the pathogenetic agent of Corona Virus Induced Disease (COVID)19. The virus enters the human cells after binding to the angiotensin converting enzyme (ACE)2 receptor in target tissues. ACE2 expression is induced in response to inflammation. The c...

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Detalles Bibliográficos
Autores principales:	Biagioli, Michele, Marchianò, Silvia, Roselli, Rosalinda, Di Giorgio, Cristina, Bellini, Rachele, Bordoni, Martina, Gidari, Anna, Sabbatini, Samuele, Francisci, Daniela, Fiorillo, Bianca, Catalanotti, Bruno, Distrutti, Eleonora, Carino, Adriana, Zampella, Angela, Costantino, Gabriele, Fiorucci, Stefano
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier Inc. 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8052506/ https://www.ncbi.nlm.nih.gov/pubmed/33872570 http://dx.doi.org/10.1016/j.bcp.2021.114564

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