DLL3 (delta-like protein 3) expression correlates with stromal desmoplasia and lymph node metastases in medullary thyroid carcinomas

Medullary thyroid carcinomas (MTC) are rare and aggressive neuroendocrine tumors of the thyroid. About 70% of MTC are sporadic; approximately 50% of those harbor somatic RET mutation. DLL3 is widely expressed in many neuroendocrine tumors and has been evaluated as a potential therapeutic target. Sin...

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Detalles Bibliográficos
Autores principales: Ingenwerth, M, Brandenburg, T, Führer-Sakel, D, Goetz, M, Weber, F, Dralle, H, Schildhaus, H-U, Schmid, K W, Theurer, S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bioscientifica Ltd 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8052580/
https://www.ncbi.nlm.nih.gov/pubmed/33617464
http://dx.doi.org/10.1530/EC-20-0611

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8052580/
https://www.ncbi.nlm.nih.gov/pubmed/33617464
http://dx.doi.org/10.1530/EC-20-0611

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