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Association of Sonic Hedgehog with the extracellular matrix requires its zinc-coordination center
BACKGROUND: Sonic Hedgehog (Shh) has a catalytic cleft characteristic for zinc metallopeptidases and has significant sequence similarities with some bacterial peptidoglycan metallopeptidases defining a subgroup within the M15A family that, besides having the characteristic zinc coordination motif, c...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8052667/ https://www.ncbi.nlm.nih.gov/pubmed/33863273 http://dx.doi.org/10.1186/s12860-021-00359-5 |