Intra-patient comparison of physiologic (68)Ga-PSMA-11 and (18)F-DCFPyL PET/CT uptake in ganglia in prostate cancer patients: a pictorial essay

BACKGROUND: Recent studies reported metabolic uptake in at least one of the evaluated ganglia in 98.5% of patients undergoing (68)Ga -PSMA-11 and in 96.9% of patients undergoing (18)F-DCFPyL PET/CT examination. We have observed different patterns of ganglion visualization with (18)F-DCFPyL compared...

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Autores principales: Osman, Medhat M., Iravani, Amir, Hofman, Michael S., Hicks, Rodney J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Case Series
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8052677/
https://www.ncbi.nlm.nih.gov/pubmed/33863390
http://dx.doi.org/10.1186/s40644-021-00404-8
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author Osman, Medhat M.
Iravani, Amir
Hofman, Michael S.
Hicks, Rodney J.
author_facet Osman, Medhat M.
Iravani, Amir
Hofman, Michael S.
Hicks, Rodney J.
author_sort Osman, Medhat M.
collection PubMed
description BACKGROUND: Recent studies reported metabolic uptake in at least one of the evaluated ganglia in 98.5% of patients undergoing (68)Ga -PSMA-11 and in 96.9% of patients undergoing (18)F-DCFPyL PET/CT examination. We have observed different patterns of ganglion visualization with (18)F-DCFPyL compared to (68)Ga-PSMA-11. This includes more frequent visualization of cervical and sacral ganglia, which may be attributable to better imaging characteristics with (18)F PET imaging. CASE PRESENTATION: This pictorial essay is to illustrate and compare, in the same patient, various representative cases of (68)Ga-PSMA-11 and (18)F-DCFPyL PET/CT uptake in ganglia at different anatomic locations, with different patterns and distribution of metabolic activity. CONCLUSION: Reading physicians should be aware of the frequently encountered and occasionally different physiologic uptake of (68)Ga-PSMA-11 and (18)F DCFPyL in different ganglia.
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spelling pubmed-80526772021-04-19 Intra-patient comparison of physiologic (68)Ga-PSMA-11 and (18)F-DCFPyL PET/CT uptake in ganglia in prostate cancer patients: a pictorial essay Osman, Medhat M. Iravani, Amir Hofman, Michael S. Hicks, Rodney J. Cancer Imaging Case Series BACKGROUND: Recent studies reported metabolic uptake in at least one of the evaluated ganglia in 98.5% of patients undergoing (68)Ga -PSMA-11 and in 96.9% of patients undergoing (18)F-DCFPyL PET/CT examination. We have observed different patterns of ganglion visualization with (18)F-DCFPyL compared to (68)Ga-PSMA-11. This includes more frequent visualization of cervical and sacral ganglia, which may be attributable to better imaging characteristics with (18)F PET imaging. CASE PRESENTATION: This pictorial essay is to illustrate and compare, in the same patient, various representative cases of (68)Ga-PSMA-11 and (18)F-DCFPyL PET/CT uptake in ganglia at different anatomic locations, with different patterns and distribution of metabolic activity. CONCLUSION: Reading physicians should be aware of the frequently encountered and occasionally different physiologic uptake of (68)Ga-PSMA-11 and (18)F DCFPyL in different ganglia. BioMed Central 2021-04-16 /pmc/articles/PMC8052677/ /pubmed/33863390 http://dx.doi.org/10.1186/s40644-021-00404-8 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Case Series
Osman, Medhat M.
Iravani, Amir
Hofman, Michael S.
Hicks, Rodney J.
Intra-patient comparison of physiologic (68)Ga-PSMA-11 and (18)F-DCFPyL PET/CT uptake in ganglia in prostate cancer patients: a pictorial essay
title Intra-patient comparison of physiologic (68)Ga-PSMA-11 and (18)F-DCFPyL PET/CT uptake in ganglia in prostate cancer patients: a pictorial essay
title_full Intra-patient comparison of physiologic (68)Ga-PSMA-11 and (18)F-DCFPyL PET/CT uptake in ganglia in prostate cancer patients: a pictorial essay
title_fullStr Intra-patient comparison of physiologic (68)Ga-PSMA-11 and (18)F-DCFPyL PET/CT uptake in ganglia in prostate cancer patients: a pictorial essay
title_full_unstemmed Intra-patient comparison of physiologic (68)Ga-PSMA-11 and (18)F-DCFPyL PET/CT uptake in ganglia in prostate cancer patients: a pictorial essay
title_short Intra-patient comparison of physiologic (68)Ga-PSMA-11 and (18)F-DCFPyL PET/CT uptake in ganglia in prostate cancer patients: a pictorial essay
title_sort intra-patient comparison of physiologic (68)ga-psma-11 and (18)f-dcfpyl pet/ct uptake in ganglia in prostate cancer patients: a pictorial essay
topic Case Series
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8052677/
https://www.ncbi.nlm.nih.gov/pubmed/33863390
http://dx.doi.org/10.1186/s40644-021-00404-8
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