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Interleukin-35 inhibited the production of histamine and pro-inflammatory cytokines through suppression MAPKs pathway in HMC-1 cells

BACKGROUND: IL-35 is a newly anti-inflammatory cytokine that belongs to the IL-12 family. Mast cells, as one of the major effector cells in the immune response system, plays an important role in the pathogenesis of chronic spontaneous urticarial (CSU). Our study aims to explore the inhibited role of...

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Detalles Bibliográficos
Autores principales: Fu, Li-xin, Chen, Tao, Sun, Qiao-mei, Zhou, Pei-mei, Guo, Zai-pei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8052689/
https://www.ncbi.nlm.nih.gov/pubmed/33865428
http://dx.doi.org/10.1186/s13223-021-00543-4