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Stability of BSE infectivity towards heat treatment even after proteolytic removal of prion protein

The unconventional infectious agents of transmissible spongiform encephalopathies (TSEs) are prions. Their infectivity co-appears with PrP(Sc), aberrant depositions of the host’s cellular prion protein (PrP(C)). Successive heat treatment in the presence of detergent and proteolysis by a keratinase f...

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Detalles Bibliográficos
Autores principales:	Langeveld, Jan P. M., Balkema-Buschmann, Anne, Becher, Dieter, Thomzig, Achim, Nonno, Romolo, Andréoletti, Olivier, Davidse, Aart, Di Bari, Michele A., Pirisinu, Laura, Agrimi, Umberto, Groschup, Martin H., Beekes, Michael, Shih, Jason
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8052740/ https://www.ncbi.nlm.nih.gov/pubmed/33863379 http://dx.doi.org/10.1186/s13567-021-00928-8

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