Cargando…

Transcriptomic biomarker pathways associated with death in HIV-infected patients with cryptococcal meningitis

BACKGROUND: Cryptococcal meningitis (CM) is a major cause of death in HIV-infected patients in sub-Saharan Africa. Many CM patients experience cryptococcosis-associated immune reconstitution inflammatory syndrome (C-IRIS), which is often fatal. We sought to identify transcriptomic biomarker pathways...

Descripción completa

Detalles Bibliográficos
Autores principales:	Vlasova-St Louis, Irina, Musubire, Abdu K., Meya, David B., Nabeta, Henry W., Mohei, Hesham, Boulware, David R., Bohjanen, Paul R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8052789/ https://www.ncbi.nlm.nih.gov/pubmed/33863324 http://dx.doi.org/10.1186/s12920-021-00914-1

Ejemplares similares

Blood neutrophil counts in HIV-infected patients with cryptococcal meningitis: Association with mortality
por: Musubire, Abdu Kisekka, et al.
Publicado: (2018)

Hearing Loss in Cryptococcal Meningitis Survivors
por: Lofgren, Sarah, et al.
Publicado: (2017)

Gastrointestinal cryptococcoma – Immune reconstitution inflammatory syndrome or cryptococcal relapse in a patient with AIDS?
por: Musubire, Abdu K., et al.
Publicado: (2015)

Clinical Features and Serum Biomarkers in HIV Immune Reconstitution Inflammatory Syndrome after Cryptococcal Meningitis: A Prospective Cohort Study
por: Boulware, David R., et al.
Publicado: (2010)

Standardized Electrolyte Supplementation and Fluid Management Improves Survival During Amphotericin Therapy for Cryptococcal Meningitis in Resource-Limited Settings
por: Bahr, Nathan C., et al.
Publicado: (2014)

Cerebrospinal Fluid Culture Positivity and Clinical Outcomes After Amphotericin-Based Induction Therapy for Cryptococcal Meningitis
por: Rolfes, Melissa A., et al.
Publicado: (2015)

The Effect of Therapeutic Lumbar Punctures on Acute Mortality From Cryptococcal Meningitis
por: Rolfes, Melissa A., et al.
Publicado: (2014)

Correlation between Blood and CSF Compartment Cytokines and Chemokines in Subjects with Cryptococcal Meningitis
por: Okafor, Elizabeth C., et al.
Publicado: (2020)

Long Term 5-Year Survival of Persons with Cryptococcal Meningitis or Asymptomatic Subclinical Antigenemia in Uganda
por: Butler, Elissa K., et al.
Publicado: (2012)

Cerebral Oximetry for Detecting High-mortality Risk Patients with Cryptococcal Meningitis
por: Diehl, John W, et al.
Publicado: (2018)

1716. Baseline Serum C-Reactive Protein Level Predicts Mortality in Cryptococcal Meningitis
por: Chesdachai, Supavit, et al.
Publicado: (2019)

Efficacy of Adjunctive Sertraline for the Treatment of HIV-Associated Cryptococcal Meningitis: an open-label dose-ranging study
por: Rhein, Joshua, et al.
Publicado: (2016)

Detrimental Outcomes of Unmasking Cryptococcal Meningitis With Recent ART Initiation
por: Rhein, Joshua, et al.
Publicado: (2018)

1472 Epidemiology of Meningitis in an HIV-infected Ugandan Cohort
por: Rajasingham, Radha, et al.
Publicado: (2014)

Hyponatremia as a Predictor of Cryptococcal Meningitis and Death Among Asymptomatic Persons With HIV and Cryptococcal Antigenemia
por: Lehman, Alice, et al.
Publicado: (2023)

Sterile Cerebrospinal Fluid Culture at Cryptococcal Meningitis Diagnosis Is Associated with High Mortality
por: Skipper, Caleb P, et al.
Publicado: (2022)

Cryptococcal Genotype Influences Immunologic Response and Human Clinical Outcome after Meningitis
por: Wiesner, Darin L., et al.
Publicado: (2012)

Association of Hyponatremia on Mortality in Cryptococcal Meningitis: A Prospective Cohort
por: Tugume, Lillian, et al.
Publicado: (2022)

Baseline Serum C-Reactive Protein Level Predicts Mortality in Cryptococcal Meningitis
por: Chesdachai, Supavit, et al.
Publicado: (2020)

Accuracy of Noninvasive Intraocular Pressure or Optic Nerve Sheath Diameter Measurements for Predicting Elevated Intracranial Pressure in Cryptococcal Meningitis
por: Nabeta, Henry W., et al.
Publicado: (2014)

Seizures in Human Immunodeficiency Virus-Associated Cryptococcal Meningitis: Predictors and Outcomes
por: Pastick, Katelyn A, et al.
Publicado: (2019)

Nosocomial Drug-Resistant Bacteremia in 2 Cohorts with Cryptococcal Meningitis, Africa
por: Rajasingham, Radha, et al.
Publicado: (2014)

Delays in Cryptococcal Meningitis Diagnosis and Care: A Mixed Methods Study in Rural Uganda
por: Link, Abigail, et al.
Publicado: (2022)

Adherence of health workers to guidelines for screening and management of cryptococcal meningitis in Uganda
por: Namuju, Olivie C., et al.
Publicado: (2023)

B Cell Compartmentalization in Blood and Cerebrospinal Fluid of HIV-Infected Ugandans with Cryptococcal Meningitis
por: Okurut, Samuel, et al.
Publicado: (2020)

Therapeutic Lumbar Punctures in Human Immunodeficiency Virus–Associated Cryptococcal Meningitis: Should Opening Pressure Direct Management?
por: Kagimu, Enock, et al.
Publicado: (2022)

Tuberculosis in HIV-Associated Cryptococcal Meningitis is Associated with an Increased Risk of Death
por: Rutakingirwa, Morris K., et al.
Publicado: (2020)

Acute Kidney Injury and Urinary Biomarkers in Human Immunodeficiency Virus–Associated Cryptococcal Meningitis
por: Schutz, Charlotte, et al.
Publicado: (2017)

869. Oral Encochleated Amphotericin B for Cryptococcal Meningitis: a Phase II Randomized Trial
por: Atukunda, Mucunguzi, et al.
Publicado: (2022)

Impact of a Cryptococcal meningitis diagnosis and treatment program at Lira Regional Referral Hospital in rural, Northern Uganda
por: Link, Abigail, et al.
Publicado: (2022)

Cryptococcal Meningitis Treatment Strategies in Resource-Limited Settings: A Cost-Effectiveness Analysis
por: Rajasingham, Radha, et al.
Publicado: (2012)

A Systematic Review of Non-Traumatic Spinal Cord Injuries in Sub-Saharan Africa and a Proposed Diagnostic Algorithm for Resource-Limited Settings
por: Musubire, Abdu Kisekka, et al.
Publicado: (2017)

Epidemiology of non-traumatic spinal cord injury in Uganda: a single center, prospective study with MRI evaluation
por: Musubire, Abdu K., et al.
Publicado: (2019)

High Burden of Cryptococcal Meningitis Among Antiretroviral Therapy–Experienced Human Immunodeficiency Virus–Infected Patients in Northern Uganda in the Era of “Test and Treat”: Implications for Cryptococcal Screening Programs
por: Okwir, Mark, et al.
Publicado: (2022)

Unmasking cryptococcal meningitis immune reconstitution inflammatory syndrome in pregnancy induced by HIV antiretroviral therapy with postpartum paradoxical exacerbation
por: Kiggundu, Reuben, et al.
Publicado: (2014)

Immune Reconstitution Disorders: Spotlight on Interferons
por: Mohei, Hesham, et al.
Publicado: (2019)

88462 Fluconazole distribution in CNS and gynecological tissues in HIV-related cryptococcal meningitis decedents
por: Nicol, Melanie R., et al.
Publicado: (2021)

Baseline Cytomegalovirus Viremia at Cryptococcal Meningitis Diagnosis Is Associated With Long-term Increased Incident TB Disease and Mortality in a Prospective Cohort of Ugandan Adults With HIV
por: Ellis, Jayne, et al.
Publicado: (2023)

1468 Detection of High CSF Levels of (1 → 3)-Beta-D-Glucan in Cryptococcal Meningitis
por: Rhein, Joshua, et al.
Publicado: (2014)

Cellular Immune Activation in Cerebrospinal Fluid From Ugandans With Cryptococcal Meningitis and Immune Reconstitution Inflammatory Syndrome
por: Meya, David B., et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_dv4hh4nlg4rka813t0gikl9pll