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Identification and functional study of GATA4 gene regulatory variants in type 2 diabetes mellitus

BACKGROUND: Type 2 diabetes mellitus (T2D) is a common and complex disease. Dysfunction of pancreatic β cells, which cannot release sufficient insulin, plays a central role in T2D. Genetics plays a critical role in T2D etiology. Transcription factor GATA4 is required for the pancreatic development,...

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Detalles Bibliográficos
Autores principales:	Ding, Liangcai, Cai, Mengdi, Chen, Lu, Yan, Han, Lu, Shicheng, Pang, Shuchao, Yan, Bo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8052808/ https://www.ncbi.nlm.nih.gov/pubmed/33865372 http://dx.doi.org/10.1186/s12902-021-00739-0

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