Oligomeric quaternary structure of Escherichia coli and Mycobacterium smegmatis Lhr helicases is nucleated by a novel C-terminal domain composed of five winged-helix modules

Mycobacterium smegmatis Lhr (MsmLhr; 1507-aa) is the founder of a novel clade of bacterial helicases. MsmLhr consists of an N-terminal helicase domain (aa 1–856) with a distinctive tertiary structure (Lhr-Core) and a C-terminal domain (Lhr-CTD) of unknown structure. Here, we report that Escherichia...

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Detalles Bibliográficos
Autores principales: Warren, Garrett M, Wang, Juncheng, Patel, Dinshaw J, Shuman, Stewart
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8053096/
https://www.ncbi.nlm.nih.gov/pubmed/33744958
http://dx.doi.org/10.1093/nar/gkab145

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8053096/
https://www.ncbi.nlm.nih.gov/pubmed/33744958
http://dx.doi.org/10.1093/nar/gkab145

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