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Regulation of ex-translational activities is the primary function of the multi-tRNA synthetase complex

During mRNA translation, tRNAs are charged by aminoacyl-tRNA synthetases and subsequently used by ribosomes. A multi-enzyme aminoacyl-tRNA synthetase complex (MSC) has been proposed to increase protein synthesis efficiency by passing charged tRNAs to ribosomes. An alternative function is that the MS...

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Detalles Bibliográficos
Autores principales: Cui, Haissi, Kapur, Mridu, Diedrich, Jolene K, Yates, John R, Ackerman, Susan L, Schimmel, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8053116/
https://www.ncbi.nlm.nih.gov/pubmed/33341895
http://dx.doi.org/10.1093/nar/gkaa1183