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Regulation of RNA editing by intracellular acidification

The hydrolytic deamination of adenosine-to-inosine (A-to-I) by RNA editing is a widespread post-transcriptional modification catalyzed by the adenosine deaminase acting on RNA (ADAR) family of proteins. ADAR-mediated RNA editing modulates cellular pathways involved in innate immunity, RNA splicing,...

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Detalles Bibliográficos
Autores principales: Malik, Turnee N, Doherty, Erin E, Gaded, Vandana M, Hill, Theodore M, Beal, Peter A, Emeson, Ronald B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8053123/
https://www.ncbi.nlm.nih.gov/pubmed/33721028
http://dx.doi.org/10.1093/nar/gkab157