Cargando…

Regulation of RNA editing by intracellular acidification

The hydrolytic deamination of adenosine-to-inosine (A-to-I) by RNA editing is a widespread post-transcriptional modification catalyzed by the adenosine deaminase acting on RNA (ADAR) family of proteins. ADAR-mediated RNA editing modulates cellular pathways involved in innate immunity, RNA splicing,...

Descripción completa

Detalles Bibliográficos
Autores principales:	Malik, Turnee N, Doherty, Erin E, Gaded, Vandana M, Hill, Theodore M, Beal, Peter A, Emeson, Ronald B
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2021
Materias:	Nucleic Acid Enzymes
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8053123/ https://www.ncbi.nlm.nih.gov/pubmed/33721028 http://dx.doi.org/10.1093/nar/gkab157

Ejemplares similares

DNA editing in DNA/RNA hybrids by adenosine deaminases that act on RNA
por: Zheng, Yuxuan, et al.
Publicado: (2017)

Recognition of duplex RNA by the deaminase domain of the RNA editing enzyme ADAR2
por: Phelps, Kelly J., et al.
Publicado: (2015)

Nucleoside analog studies indicate mechanistic differences between RNA-editing adenosine deaminases
por: Mizrahi, Rena A., et al.
Publicado: (2012)

The ADAR RNA editing enzyme controls neuronal excitability in Drosophila melanogaster
por: Li, Xianghua, et al.
Publicado: (2014)

Impact of alanyl-tRNA synthetase editing deficiency in yeast
por: Zhang, Hong, et al.
Publicado: (2021)

Probing RNA recognition by human ADAR2 using a high-throughput mutagenesis method
por: Wang, Yuru, et al.
Publicado: (2016)

Oxidation alters the architecture of the phenylalanyl-tRNA synthetase editing domain to confer hyperaccuracy
por: Srinivas, Pooja, et al.
Publicado: (2021)

A threonyl-tRNA synthetase-like protein has tRNA aminoacylation and editing activities
por: Chen, Yun, et al.
Publicado: (2018)

Negative catalysis by the editing domain of class I aminoacyl-tRNA synthetases
por: Zivkovic, Igor, et al.
Publicado: (2022)

Editing of misaminoacylated tRNA controls the sensitivity of amino acid stress responses in Saccharomyces cerevisiae
por: Mohler, Kyle, et al.
Publicado: (2017)

RNA Editing TUTase 1: structural foundation of substrate recognition, complex interactions and drug targeting
por: Rajappa-Titu, Lional, et al.
Publicado: (2016)

Nitrosative stress inhibits aminoacylation and editing activities of mitochondrial threonyl-tRNA synthetase by S-nitrosation
por: Zheng, Wen-Qiang, et al.
Publicado: (2020)

Modular pathways for editing non-cognate amino acids by human cytoplasmic leucyl-tRNA synthetase
por: Chen, Xin, et al.
Publicado: (2011)

Crucial role of the C-terminal domain of Mycobacterium tuberculosis leucyl-tRNA synthetase in aminoacylation and editing
por: Hu, Qing-Hua, et al.
Publicado: (2013)

Stereospecificity control in aminoacyl-tRNA-synthetases: new evidence of d-amino acids activation and editing
por: Rybak, Mariia Yu, et al.
Publicado: (2019)

Asymmetric dimerization of adenosine deaminase acting on RNA facilitates substrate recognition
por: Thuy-Boun, Alexander S, et al.
Publicado: (2020)

A protein–protein interaction underlies the molecular basis for substrate recognition by an adenosine-to-inosine RNA-editing enzyme
por: Rajendren, Suba, et al.
Publicado: (2018)

Self-protective responses to norvaline-induced stress in a leucyl-tRNA synthetase editing-deficient yeast strain
por: Ji, Quan-Quan, et al.
Publicado: (2017)

Intracellular selection of trans-cleaving hammerhead ribozymes
por: Huang, Xin, et al.
Publicado: (2019)

RNA binding candidates for human ADAR3 from substrates of a gain of function mutant expressed in neuronal cells
por: Wang, Yuru, et al.
Publicado: (2019)

Coordination between aminoacylation and editing to protect against proteotoxicity
por: Zhang, Hong, et al.
Publicado: (2023)

Enhanced Cas12a editing in mammalian cells and zebrafish
por: Liu, Pengpeng, et al.
Publicado: (2019)

Editing activity for eliminating mischarged tRNAs is essential in mammalian mitochondria
por: Hilander, Taru, et al.
Publicado: (2018)

In-depth assessment of the PAM compatibility and editing activities of Cas9 variants
por: Zhang, Weiwei, et al.
Publicado: (2021)

Transcriptional supercoiling boosts topoisomerase II-mediated knotting of intracellular DNA
por: Valdés, Antonio, et al.
Publicado: (2019)

Progressive engineering of a homing endonuclease genome editing reagent for the murine X-linked immunodeficiency locus
por: Wang, Yupeng, et al.
Publicado: (2014)

Regulation of the catalytic function of topoisomerase II alpha through association with RNA
por: Park, Seung-Won, et al.
Publicado: (2008)

Discovery of potent and versatile CRISPR–Cas9 inhibitors engineered for chemically controllable genome editing
por: Song, Guoxu, et al.
Publicado: (2022)

A novel TALE nuclease scaffold enables high genome editing activity in combination with low toxicity
por: Mussolino, Claudio, et al.
Publicado: (2011)

Bi-PE: bi-directional priming improves CRISPR/Cas9 prime editing in mammalian cells
por: Tao, Rui, et al.
Publicado: (2022)

Antisense RNA associated with biological regulation of a restriction–modification system
por: Mruk, Iwona, et al.
Publicado: (2011)

Polyadenylation helps regulate functional tRNA levels in Escherichia coli
por: Mohanty, Bijoy K., et al.
Publicado: (2012)

A ‘new lease of life’: FnCpf1 possesses DNA cleavage activity for genome editing in human cells
por: Tu, Mengjun, et al.
Publicado: (2017)

A tRNA splicing operon: Archease endows RtcB with dual GTP/ATP cofactor specificity and accelerates RNA ligation
por: Desai, Kevin K., et al.
Publicado: (2014)

RNA–DNA and DNA–DNA base-pairing at the upstream edge of the transcription bubble regulate translocation of RNA polymerase and transcription rate
por: KIreeva, Maria, et al.
Publicado: (2018)

Allosteric regulation of helicase core activities of the DEAD-box helicase YxiN by RNA binding to its RNA recognition motif
por: Samatanga, Brighton, et al.
Publicado: (2017)

METTL4 catalyzes m(6)Am methylation in U2 snRNA to regulate pre-mRNA splicing
por: Goh, Yeek Teck, et al.
Publicado: (2020)

AID–RNA polymerase II transcription-dependent deamination of IgV DNA
por: Pham, Phuong, et al.
Publicado: (2019)

The siRNA suppressor RTL1 is redox-regulated through glutathionylation of a conserved cysteine in the double-stranded-RNA-binding domain
por: Charbonnel, Cyril, et al.
Publicado: (2017)

Single-molecule analysis of 1D diffusion and transcription elongation of T7 RNA polymerase along individual stretched DNA molecules
por: Kim, Ji Hoon, et al.
Publicado: (2007)

Cannot write session to /tmp/vufind_sessions/sess_end39cqeao6eqgqrk1cchtg1cu