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FGF23 ameliorates ischemia-reperfusion induced acute kidney injury via modulation of endothelial progenitor cells: targeting SDF-1/CXCR4 signaling

The levels of fibroblast growth factor 23 (FGF23) rapidly increases after acute kidney injury (AKI). However, the role of FGF23 in AKI is still unclear. Here, we observe that pretreatment with FGF23 protein into ischemia-reperfusion induced AKI mice ameliorates kidney injury by promoting renal tubul...

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Detalles Bibliográficos
Autores principales: Chang, Huang-Ming, Peng, Kang-Yung, Chan, Chieh-Kai, Sun, Chiao-Yin, Chen, Ying-Ying, Chang, Han-Mei, Huang, Chun-Lin, Liu, Pei-Chun, Chen, Peng-Ying, Wang, Kuo-Chuan, Wang, Wei-Jie, Wu, Chen-Chi, Lin, Yu-Feng, Lai, Tai-Shuan, Huang, Tao-Min, Young, Guang-Huar, Lin, Shuei-Liong, Ostermann, Marlies, Chu, Tzong-Shinn, Chueh, Jeff S., Wu, Vin-Cent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8053200/
https://www.ncbi.nlm.nih.gov/pubmed/33866326
http://dx.doi.org/10.1038/s41419-021-03693-w