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IL-23 skin and joint profiling in psoriatic arthritis: novel perspectives in understanding clinical responses to IL-23 inhibitors

OBJECTIVES: To determine the relationship between synovial versus skin transcriptional/histological profiles in patients with active psoriatic arthritis (PsA) and explore mechanistic links between diseased tissue pathology and clinical outcomes. METHODS: Twenty-seven active PsA patients were enrolle...

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Detalles Bibliográficos
Autores principales: Nerviani, Alessandra, Boutet, Marie-Astrid, Tan, Wang Sin Gina, Goldmann, Katriona, Purkayastha, Nirupam, Lajtos, Tamas Ajtos, Hands, Rebecca, Lewis, Myles, Kelly, Stephen, Pitzalis, Costantino
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8053336/
https://www.ncbi.nlm.nih.gov/pubmed/33243781
http://dx.doi.org/10.1136/annrheumdis-2020-218186

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