Large-scale meta-analysis across East Asian and European populations updated genetic architecture and variant-driven biology of rheumatoid arthritis, identifying 11 novel susceptibility loci

OBJECTIVES: Nearly 110 susceptibility loci for rheumatoid arthritis (RA) with modest effect sizes have been identified by population-based genetic association studies, suggesting a large number of undiscovered variants behind a highly polygenic genetic architecture of RA. Here, we performed the larg...

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Detalles Bibliográficos
Autores principales: Ha, Eunji, Bae, Sang-Cheol, Kim, Kwangwoo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Rheumatoid Arthritis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8053349/
https://www.ncbi.nlm.nih.gov/pubmed/33310728
http://dx.doi.org/10.1136/annrheumdis-2020-219065

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8053349/
https://www.ncbi.nlm.nih.gov/pubmed/33310728
http://dx.doi.org/10.1136/annrheumdis-2020-219065

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