Treatment with senicapoc in a porcine model of acute respiratory distress syndrome

BACKGROUND: Senicapoc is a potent and selective blocker of KCa3.1, a calcium-activated potassium channel of intermediate conductance. In the present study, we investigated whether there is a beneficial effect of senicapoc in a large animal model of acute respiratory distress syndrome (ARDS). The pri...

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Detalles Bibliográficos
Autores principales: Petersen, Asbjørn G., Lind, Peter C., Jensen, Anne-Sophie B., Eggertsen, Mark A., Granfeldt, Asger, Simonsen, Ulf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8053424/
https://www.ncbi.nlm.nih.gov/pubmed/33870468
http://dx.doi.org/10.1186/s40635-021-00381-z

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