A Narrative Review of Gut-Muscle Axis and Sarcopenia: The Potential Role of Gut Microbiota

Sarcopenia is a multifactorial disease related to aging, chronic inflammation, insufficient nutrition, and physical inactivity. Previous studies have suggested that there is a relationship between sarcopenia and gut microbiota,namely, the gut-muscle axis. The present review highlights that the gut m...

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Detalles Bibliográficos
Autores principales: Zhao, Jiaxi, Huang, Yiqin, Yu, Xiaofeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8053521/
https://www.ncbi.nlm.nih.gov/pubmed/33880058
http://dx.doi.org/10.2147/IJGM.S301141
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author Zhao, Jiaxi
Huang, Yiqin
Yu, Xiaofeng
author_facet Zhao, Jiaxi
Huang, Yiqin
Yu, Xiaofeng
author_sort Zhao, Jiaxi
collection PubMed
description Sarcopenia is a multifactorial disease related to aging, chronic inflammation, insufficient nutrition, and physical inactivity. Previous studies have suggested that there is a relationship between sarcopenia and gut microbiota,namely, the gut-muscle axis. The present review highlights that the gut microbiota can affect muscle mass and muscle function from inflammation and immunity,substance and energy metabolism, endocrine and insulin sensitivity, etc., directly or indirectly establishing a connection with sarcopenia, thereby realizing the “gut-muscle axis”.
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spelling pubmed-80535212021-04-19 A Narrative Review of Gut-Muscle Axis and Sarcopenia: The Potential Role of Gut Microbiota Zhao, Jiaxi Huang, Yiqin Yu, Xiaofeng Int J Gen Med Review Sarcopenia is a multifactorial disease related to aging, chronic inflammation, insufficient nutrition, and physical inactivity. Previous studies have suggested that there is a relationship between sarcopenia and gut microbiota,namely, the gut-muscle axis. The present review highlights that the gut microbiota can affect muscle mass and muscle function from inflammation and immunity,substance and energy metabolism, endocrine and insulin sensitivity, etc., directly or indirectly establishing a connection with sarcopenia, thereby realizing the “gut-muscle axis”. Dove 2021-04-13 /pmc/articles/PMC8053521/ /pubmed/33880058 http://dx.doi.org/10.2147/IJGM.S301141 Text en © 2021 Zhao et al. https://creativecommons.org/licenses/by-nc/3.0/This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/ (https://creativecommons.org/licenses/by-nc/3.0/) ). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).
spellingShingle Review
Zhao, Jiaxi
Huang, Yiqin
Yu, Xiaofeng
A Narrative Review of Gut-Muscle Axis and Sarcopenia: The Potential Role of Gut Microbiota
title A Narrative Review of Gut-Muscle Axis and Sarcopenia: The Potential Role of Gut Microbiota
title_full A Narrative Review of Gut-Muscle Axis and Sarcopenia: The Potential Role of Gut Microbiota
title_fullStr A Narrative Review of Gut-Muscle Axis and Sarcopenia: The Potential Role of Gut Microbiota
title_full_unstemmed A Narrative Review of Gut-Muscle Axis and Sarcopenia: The Potential Role of Gut Microbiota
title_short A Narrative Review of Gut-Muscle Axis and Sarcopenia: The Potential Role of Gut Microbiota
title_sort narrative review of gut-muscle axis and sarcopenia: the potential role of gut microbiota
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8053521/
https://www.ncbi.nlm.nih.gov/pubmed/33880058
http://dx.doi.org/10.2147/IJGM.S301141
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