Cargando…

MAdCAM-1/α4β7 Integrin-Mediated Lymphocyte/Endothelium Interactions Exacerbate Acute Immune-Mediated Hepatitis in Mice

BACKGROUND & AIMS: Aberrant lymphocyte homing could potentially link inflammatory processes in the intestine and the liver, as distinct hepatobiliary diseases frequently develop as extra-intestinal manifestations in inflammatory bowel disease. In this study, we examined the role of the gut-tropi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Schippers, Angela, Hübel, Jessica, Heymann, Felix, Clahsen, Thomas, Eswaran, Sreepradha, Schlepütz, Sarah, Püllen, Robin, Gaßler, Nikolaus, Tenbrock, Klaus, Tacke, Frank, Wagner, Norbert
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2020
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8053699/ https://www.ncbi.nlm.nih.gov/pubmed/33316453 http://dx.doi.org/10.1016/j.jcmgh.2020.12.003

Ejemplares similares

MAdCAM-1-Mediated Intestinal Lymphocyte Homing Is Critical for the Development of Active Experimental Autoimmune Encephalomyelitis
por: Kuhbandner, Kristina, et al.
Publicado: (2019)

Vedolizumab blocks α4β7 integrin-mediated T cell adhesion to MAdCAM-1 in microscopic colitis
por: Besendorf, Laura, et al.
Publicado: (2022)

MAdCAM costimulation through Integrin-α(4)β(7) promotes HIV replication
por: Nawaz, Fatima, et al.
Publicado: (2018)

The Force-Dependent Mechanism of an Integrin α4β7–MAdCAM-1 Interaction
por: Su, Youmin, et al.
Publicado: (2023)

Force-Regulated Calcium Signaling of Lymphoid Cell RPMI 8226 Mediated by Integrin α(4)β(7)/MAdCAM-1 in Flow
por: Sun, Dongshan, et al.
Publicado: (2023)

β7-Integrin exacerbates experimental DSS-induced colitis in mice by directing inflammatory monocytes into the colon
por: Schippers, A, et al.
Publicado: (2016)

Inflammatory cytokines induce MAdCAM-1 in murine hepatic endothelial cells and mediate alpha-4 beta-7 integrin dependent lymphocyte endothelial adhesion In Vitro
por: Ando, Tomoaki, et al.
Publicado: (2007)

α4β7 integrin-dependent adhesion of T cells to MAdCAM-1 is blocked by vedolizumab in patients with chronic refractory pouchitis
por: Melde, Michaela, et al.
Publicado: (2021)

Development of Mucosal PNAd(+) and MAdCAM-1(+) Venules during Disease Course in Ulcerative Colitis
por: Roosenboom, Britt, et al.
Publicado: (2020)

Bile acids regulate MAdCAM-1 expression to link the gut microbiota to cancer immunosurveillance
por: Fidelle, Marine, et al.
Publicado: (2023)

TNF-α induced endothelial MAdCAM-1 expression is regulated by exogenous, not endogenous nitric oxide
por: Oshima, Tadayuki, et al.
Publicado: (2001)

Differential Effects of the Absence of Nkx2-3 and MAdCAM-1 on the Distribution of Intestinal Type 3 Innate Lymphoid Cells and Postnatal SILT Formation in Mice
por: Vojkovics, Dóra, et al.
Publicado: (2019)

The Compromised Mucosal Immune System of β7 Integrin-Deficient Mice Has Only Minor Effects on the Fecal Microbiota in Homeostasis
por: Babbar, Anshu, et al.
Publicado: (2019)

Melatonin reduces TNF-a induced expression of MAdCAM-1 via inhibition of NF-kB.
por: Sasaki, Makoto, et al.
Publicado: (2002)

Bile Acids Modulate Colonic MAdCAM-1 Expression in a Murine Model of Combined Cholestasis and Colitis
por: Gao, Rachel Y., et al.
Publicado: (2020)

Circulating MAdCAM-1 and ITGB7 in Patients with Plaque Psoriasis and Eruptive Lichen Planus—Preliminary Data
por: Baran, Anna, et al.
Publicado: (2021)

Antibody secreting cells are critically dependent on integrin α4β7/MAdCAM-1 for intestinal recruitment and control of the microbiota during chronic colitis
por: Tyler, Christopher J., et al.
Publicado: (2021)

Transfection of IL-10 expression vectors into endothelial cultures attenuates α4β7-dependent lymphocyte adhesion mediated by MAdCAM-1
por: Sasaki, Makoto, et al.
Publicado: (2003)

Involvement of oxidative stress and mucosal addressin cell adhesion molecule-1 (MAdCAM-1) in inflammatory bowel disease
por: Tanida, Satoshi, et al.
Publicado: (2011)

Phase II evaluation of anti-MAdCAM antibody PF-00547659 in the treatment of Crohn’s disease: report of the OPERA study
por: Sandborn, William J, et al.
Publicado: (2018)

Anti-MAdCAM-1-Conjugated Nanocarriers Delivering Quantum Dots Enable Specific Imaging of Inflammatory Bowel Disease
por: Truffi, Marta, et al.
Publicado: (2020)

Anti-MAdCAM-1 antibody (PF-00547659) for active refractory Crohn’s disease in Japanese and Korean patients: the OPERA study
por: Saruta, Masayuki, et al.
Publicado: (2020)

A Small Molecule, Which Competes with MAdCAM-1, Activates Integrin α(4)β(7) and Fails to Prevent Mucosal Transmission of SHIV-SF162P3
por: Arrode-Brusés, Géraldine, et al.
Publicado: (2016)

Anti-MAdCAM Antibody Increases ß7+ T Cells and CCR9 Gene Expression in the Peripheral Blood of Patients With Crohn’s Disease
por: Hassan-Zahraee, Mina, et al.
Publicado: (2018)

Correction: A Small Molecule, Which Competes with MAdCAM-1, Activates Integrin α(4)β(7) and Fails to Prevent Mucosal Transmission of SHIV-SF162P3
por: Arrode-Brusés, Géraldine, et al.
Publicado: (2016)

The Sphingosine-1-Phosphate (S1P) Lysophospholipid Receptor S1P(3) Regulates MAdCAM-1(+) Endothelial Cells in Splenic Marginal Sinus Organization
por: Girkontaite, Irute, et al.
Publicado: (2004)

Baseline levels of dynamic CD4(+) T cell adhesion to MAdCAM-1 correlate with clinical response to vedolizumab treatment in ulcerative colitis: a cohort study
por: Allner, Clarissa, et al.
Publicado: (2020)

Long-term Safety and Efficacy of the Anti-MAdCAM-1 Monoclonal Antibody Ontamalimab [SHP647] for the Treatment of Ulcerative Colitis: The Open-label Study TURANDOT II
por: Reinisch, Walter, et al.
Publicado: (2021)

MAdCAM-1 costimulation in the presence of retinoic acid and TGF-β promotes HIV infection and differentiation of CD4(+) T cells into CCR5(+) T(RM)-like cells
por: Vimonpatranon, Sinmanus, et al.
Publicado: (2023)

Population Pharmacokinetics and Pharmacodynamics of Ontamalimab (SHP647), a Fully Human Monoclonal Antibody Against Mucosal Addressin Cell Adhesion Molecule‐1 (MAdCAM‐1), in Patients With Ulcerative Colitis or Crohn's Disease
por: Wang, Yi, et al.
Publicado: (2020)

Integrins mediate mechanical compression–induced endothelium-dependent vasodilation through endothelial nitric oxide pathway
por: Lu, Xiao, et al.
Publicado: (2015)

Cadherins, Selectins, and Integrins in CAM-DR in Leukemia
por: Kim, Hye Na, et al.
Publicado: (2020)

Direct evidence for cell adhesion-mediated radioresistance (CAM-RR) on the level of individual integrin β1 clusters
por: Babel, Laura, et al.
Publicado: (2017)

Upregulation of Anti-Oxidative Stress Response Improves Metabolic Changes in L-Selectin-Deficient Mice but Does Not Prevent NAFLD Progression or Fecal Microbiota Shifts
por: Eswaran, Sreepradha, et al.
Publicado: (2021)

Integrin-mediated mechanotransduction
por: Sun, Zhiqi, et al.
Publicado: (2016)

Liver endothelium mediates the hepatocyte's uptake of ceruloplasmin
Publicado: (1986)

CD11c-Specific Deletion Reveals CREB as a Critical Regulator of DC Function during the Germinal Center Response
por: Ohl, Kim, et al.
Publicado: (2018)

Spindle checkpoint proteins Mad1 and Mad2 are required for cytostatic factor–mediated metaphase arrest
por: Tunquist, Brian J., et al.
Publicado: (2003)

Spindle assembly checkpoint robustness requires Tpr-mediated regulation of Mad1/Mad2 proteostasis
por: Schweizer, Nina, et al.
Publicado: (2013)

Monocyte rolling, arrest and spreading on IL-4-activated vascular endothelium under flow is mediated via sequential action of L-selectin, beta 1-integrins, and beta 2-integrins
Publicado: (1994)

Cannot write session to /tmp/vufind_sessions/sess_b78ri6vemplo04d93g2sclti13