L-citrulline increases arginase II protein levels and arginase activity in hypoxic piglet pulmonary artery endothelial cells

The L-arginine precursor, L-citrulline, re-couples endothelial nitric oxide synthase, increases nitric oxide production, and ameliorates chronic hypoxia-induced pulmonary hypertension in newborn pigs. L-arginine can induce arginase, which, in turn, may diminish nitric oxide production. Our major pur...

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Detalles Bibliográficos
Autores principales: Douglass, Matthew S., Zhang, Yongmei, Kaplowitz, Mark R., Fike, Candice D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8053766/
https://www.ncbi.nlm.nih.gov/pubmed/33948161
http://dx.doi.org/10.1177/20458940211006289

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