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Cotranscriptional R-loop formation by Mfd involves topological partitioning of DNA
R-loops are nucleic acid hybrids which form when an RNA invades duplex DNA to pair with its template sequence. Although they are implicated in a growing number of gene regulatory processes, their mechanistic origins remain unclear. We here report real-time observations of cotranscriptional R-loop fo...
Autores principales: | Portman, James R., Brouwer, Gwendolyn M., Bollins, Jack, Savery, Nigel J., Strick, Terence R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8053947/ https://www.ncbi.nlm.nih.gov/pubmed/33827922 http://dx.doi.org/10.1073/pnas.2019630118 |
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