Cargando…

Confidence intervals for policy evaluation in adaptive experiments

Adaptive experimental designs can dramatically improve efficiency in randomized trials. But with adaptively collected data, common estimators based on sample means and inverse propensity-weighted means can be biased or heavy-tailed. This poses statistical challenges, in particular when the experimen...

Descripción completa

Detalles Bibliográficos
Autores principales: Hadad, Vitor, Hirshberg, David A., Zhan, Ruohan, Wager, Stefan, Athey, Susan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8054003/
https://www.ncbi.nlm.nih.gov/pubmed/33876748
http://dx.doi.org/10.1073/pnas.2014602118
_version_ 1783680227275177984
author Hadad, Vitor
Hirshberg, David A.
Zhan, Ruohan
Wager, Stefan
Athey, Susan
author_facet Hadad, Vitor
Hirshberg, David A.
Zhan, Ruohan
Wager, Stefan
Athey, Susan
author_sort Hadad, Vitor
collection PubMed
description Adaptive experimental designs can dramatically improve efficiency in randomized trials. But with adaptively collected data, common estimators based on sample means and inverse propensity-weighted means can be biased or heavy-tailed. This poses statistical challenges, in particular when the experimenter would like to test hypotheses about parameters that were not targeted by the data-collection mechanism. In this paper, we present a class of test statistics that can handle these challenges. Our approach is to adaptively reweight the terms of an augmented inverse propensity-weighting estimator to control the contribution of each term to the estimator’s variance. This scheme reduces overall variance and yields an asymptotically normal test statistic. We validate the accuracy of the resulting estimates and their CIs in numerical experiments and show that our methods compare favorably to existing alternatives in terms of mean squared error, coverage, and CI size.
format Online
Article
Text
id pubmed-8054003
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher National Academy of Sciences
record_format MEDLINE/PubMed
spelling pubmed-80540032021-05-04 Confidence intervals for policy evaluation in adaptive experiments Hadad, Vitor Hirshberg, David A. Zhan, Ruohan Wager, Stefan Athey, Susan Proc Natl Acad Sci U S A Physical Sciences Adaptive experimental designs can dramatically improve efficiency in randomized trials. But with adaptively collected data, common estimators based on sample means and inverse propensity-weighted means can be biased or heavy-tailed. This poses statistical challenges, in particular when the experimenter would like to test hypotheses about parameters that were not targeted by the data-collection mechanism. In this paper, we present a class of test statistics that can handle these challenges. Our approach is to adaptively reweight the terms of an augmented inverse propensity-weighting estimator to control the contribution of each term to the estimator’s variance. This scheme reduces overall variance and yields an asymptotically normal test statistic. We validate the accuracy of the resulting estimates and their CIs in numerical experiments and show that our methods compare favorably to existing alternatives in terms of mean squared error, coverage, and CI size. National Academy of Sciences 2021-04-13 2021-04-05 /pmc/articles/PMC8054003/ /pubmed/33876748 http://dx.doi.org/10.1073/pnas.2014602118 Text en Copyright © 2021 the Author(s). Published by PNAS. https://creativecommons.org/licenses/by-nc-nd/4.0/This open access article is distributed under Creative Commons Attribution-NonCommercial-NoDerivatives License 4.0 (CC BY-NC-ND) (https://creativecommons.org/licenses/by-nc-nd/4.0/) .
spellingShingle Physical Sciences
Hadad, Vitor
Hirshberg, David A.
Zhan, Ruohan
Wager, Stefan
Athey, Susan
Confidence intervals for policy evaluation in adaptive experiments
title Confidence intervals for policy evaluation in adaptive experiments
title_full Confidence intervals for policy evaluation in adaptive experiments
title_fullStr Confidence intervals for policy evaluation in adaptive experiments
title_full_unstemmed Confidence intervals for policy evaluation in adaptive experiments
title_short Confidence intervals for policy evaluation in adaptive experiments
title_sort confidence intervals for policy evaluation in adaptive experiments
topic Physical Sciences
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8054003/
https://www.ncbi.nlm.nih.gov/pubmed/33876748
http://dx.doi.org/10.1073/pnas.2014602118
work_keys_str_mv AT hadadvitor confidenceintervalsforpolicyevaluationinadaptiveexperiments
AT hirshbergdavida confidenceintervalsforpolicyevaluationinadaptiveexperiments
AT zhanruohan confidenceintervalsforpolicyevaluationinadaptiveexperiments
AT wagerstefan confidenceintervalsforpolicyevaluationinadaptiveexperiments
AT atheysusan confidenceintervalsforpolicyevaluationinadaptiveexperiments