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Confidence intervals for policy evaluation in adaptive experiments
Adaptive experimental designs can dramatically improve efficiency in randomized trials. But with adaptively collected data, common estimators based on sample means and inverse propensity-weighted means can be biased or heavy-tailed. This poses statistical challenges, in particular when the experimen...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8054003/ https://www.ncbi.nlm.nih.gov/pubmed/33876748 http://dx.doi.org/10.1073/pnas.2014602118 |
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author | Hadad, Vitor Hirshberg, David A. Zhan, Ruohan Wager, Stefan Athey, Susan |
author_facet | Hadad, Vitor Hirshberg, David A. Zhan, Ruohan Wager, Stefan Athey, Susan |
author_sort | Hadad, Vitor |
collection | PubMed |
description | Adaptive experimental designs can dramatically improve efficiency in randomized trials. But with adaptively collected data, common estimators based on sample means and inverse propensity-weighted means can be biased or heavy-tailed. This poses statistical challenges, in particular when the experimenter would like to test hypotheses about parameters that were not targeted by the data-collection mechanism. In this paper, we present a class of test statistics that can handle these challenges. Our approach is to adaptively reweight the terms of an augmented inverse propensity-weighting estimator to control the contribution of each term to the estimator’s variance. This scheme reduces overall variance and yields an asymptotically normal test statistic. We validate the accuracy of the resulting estimates and their CIs in numerical experiments and show that our methods compare favorably to existing alternatives in terms of mean squared error, coverage, and CI size. |
format | Online Article Text |
id | pubmed-8054003 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | National Academy of Sciences |
record_format | MEDLINE/PubMed |
spelling | pubmed-80540032021-05-04 Confidence intervals for policy evaluation in adaptive experiments Hadad, Vitor Hirshberg, David A. Zhan, Ruohan Wager, Stefan Athey, Susan Proc Natl Acad Sci U S A Physical Sciences Adaptive experimental designs can dramatically improve efficiency in randomized trials. But with adaptively collected data, common estimators based on sample means and inverse propensity-weighted means can be biased or heavy-tailed. This poses statistical challenges, in particular when the experimenter would like to test hypotheses about parameters that were not targeted by the data-collection mechanism. In this paper, we present a class of test statistics that can handle these challenges. Our approach is to adaptively reweight the terms of an augmented inverse propensity-weighting estimator to control the contribution of each term to the estimator’s variance. This scheme reduces overall variance and yields an asymptotically normal test statistic. We validate the accuracy of the resulting estimates and their CIs in numerical experiments and show that our methods compare favorably to existing alternatives in terms of mean squared error, coverage, and CI size. National Academy of Sciences 2021-04-13 2021-04-05 /pmc/articles/PMC8054003/ /pubmed/33876748 http://dx.doi.org/10.1073/pnas.2014602118 Text en Copyright © 2021 the Author(s). Published by PNAS. https://creativecommons.org/licenses/by-nc-nd/4.0/This open access article is distributed under Creative Commons Attribution-NonCommercial-NoDerivatives License 4.0 (CC BY-NC-ND) (https://creativecommons.org/licenses/by-nc-nd/4.0/) . |
spellingShingle | Physical Sciences Hadad, Vitor Hirshberg, David A. Zhan, Ruohan Wager, Stefan Athey, Susan Confidence intervals for policy evaluation in adaptive experiments |
title | Confidence intervals for policy evaluation in adaptive experiments |
title_full | Confidence intervals for policy evaluation in adaptive experiments |
title_fullStr | Confidence intervals for policy evaluation in adaptive experiments |
title_full_unstemmed | Confidence intervals for policy evaluation in adaptive experiments |
title_short | Confidence intervals for policy evaluation in adaptive experiments |
title_sort | confidence intervals for policy evaluation in adaptive experiments |
topic | Physical Sciences |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8054003/ https://www.ncbi.nlm.nih.gov/pubmed/33876748 http://dx.doi.org/10.1073/pnas.2014602118 |
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