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A rare case of urachal adenocarcinoma with bone marrow metastasis

Urachal cancer is a rare and aggressive cancer that often presents in advanced stages. Given the rarity of this malignancy, medical case studies provide one of the few sources of literature available through which clinicians can guide medical management. Surgery is widely considered to be the mainst...

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Autor principal: Van Allen, Joshua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8054045/
https://www.ncbi.nlm.nih.gov/pubmed/33858907
http://dx.doi.org/10.1136/bcr-2021-242315
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author Van Allen, Joshua
author_facet Van Allen, Joshua
author_sort Van Allen, Joshua
collection PubMed
description Urachal cancer is a rare and aggressive cancer that often presents in advanced stages. Given the rarity of this malignancy, medical case studies provide one of the few sources of literature available through which clinicians can guide medical management. Surgery is widely considered to be the mainstay of therapy when disease is localised and surgically resectable, therefore most current case studies on urachal cancer focus on surgical management, occasionally with adjuvant chemotherapy. However, few case studies discuss chemotherapy alone in the treatment of metastatic disease. Most studies indicate a median overall survival between 12 and 24 months for metastatic urachal adenocarcinoma. Bone marrow metastasis of solid tumours, when considered alone, portends a poor prognosis. The patient in this case study represents a rare case of stage IV urachal adenocarcinoma metastatic to the bone marrow without progression of disease after 6 months of treatment.
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spelling pubmed-80540452021-05-11 A rare case of urachal adenocarcinoma with bone marrow metastasis Van Allen, Joshua BMJ Case Rep Case Report Urachal cancer is a rare and aggressive cancer that often presents in advanced stages. Given the rarity of this malignancy, medical case studies provide one of the few sources of literature available through which clinicians can guide medical management. Surgery is widely considered to be the mainstay of therapy when disease is localised and surgically resectable, therefore most current case studies on urachal cancer focus on surgical management, occasionally with adjuvant chemotherapy. However, few case studies discuss chemotherapy alone in the treatment of metastatic disease. Most studies indicate a median overall survival between 12 and 24 months for metastatic urachal adenocarcinoma. Bone marrow metastasis of solid tumours, when considered alone, portends a poor prognosis. The patient in this case study represents a rare case of stage IV urachal adenocarcinoma metastatic to the bone marrow without progression of disease after 6 months of treatment. BMJ Publishing Group 2021-04-15 /pmc/articles/PMC8054045/ /pubmed/33858907 http://dx.doi.org/10.1136/bcr-2021-242315 Text en © BMJ Publishing Group Limited 2021. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) .
spellingShingle Case Report
Van Allen, Joshua
A rare case of urachal adenocarcinoma with bone marrow metastasis
title A rare case of urachal adenocarcinoma with bone marrow metastasis
title_full A rare case of urachal adenocarcinoma with bone marrow metastasis
title_fullStr A rare case of urachal adenocarcinoma with bone marrow metastasis
title_full_unstemmed A rare case of urachal adenocarcinoma with bone marrow metastasis
title_short A rare case of urachal adenocarcinoma with bone marrow metastasis
title_sort rare case of urachal adenocarcinoma with bone marrow metastasis
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8054045/
https://www.ncbi.nlm.nih.gov/pubmed/33858907
http://dx.doi.org/10.1136/bcr-2021-242315
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