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Changes in Stem Cell Transplant activity and procedures during SARS-CoV2 pandemic in Italy: an Italian Bone Marrow Transplant Group (GITMO) nationwide analysis (TransCOVID-19 Survey)

The Transplant Centers belonging to Gruppo Italiano per il Trapianto di Midollo Osseo (GITMO) conducted a survey with the aim of evaluating the effect of SARS-CoV2 pandemic on the allogeneic transplant activity in Italy. The pandemic period from 1/3/2020 to 31/7/2020 was compared with the same perio...

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Autores principales: Russo, Domenico, Polverelli, Nicola, Malagola, Michele, Farina, Mirko, Leoni, Alessandro, Bernardi, Simona, Mammoliti, Sonia, Sacchi, Nicoletta, Martino, Massimo, Ciceri, Fabio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8054130/
https://www.ncbi.nlm.nih.gov/pubmed/33875810
http://dx.doi.org/10.1038/s41409-021-01287-w
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author Russo, Domenico
Polverelli, Nicola
Malagola, Michele
Farina, Mirko
Leoni, Alessandro
Bernardi, Simona
Mammoliti, Sonia
Sacchi, Nicoletta
Martino, Massimo
Ciceri, Fabio
author_facet Russo, Domenico
Polverelli, Nicola
Malagola, Michele
Farina, Mirko
Leoni, Alessandro
Bernardi, Simona
Mammoliti, Sonia
Sacchi, Nicoletta
Martino, Massimo
Ciceri, Fabio
author_sort Russo, Domenico
collection PubMed
description The Transplant Centers belonging to Gruppo Italiano per il Trapianto di Midollo Osseo (GITMO) conducted a survey with the aim of evaluating the effect of SARS-CoV2 pandemic on the allogeneic transplant activity in Italy. The pandemic period from 1/3/2020 to 31/7/2020 was compared with the same period in 2019. Overall, in 2020 there was a 2.4% reduction in the number of allo-HCT cases compared to 2019. Interestingly, this deflection did not affect the acute leukemia cases (+5.7% in 2020). The use of peripheral blood-derived stem cells (+10.7%) and cryopreservation (97.4% of the centers) was highly adopted in 2020. Despite the sanitary emergency, almost all of the surveyed centers declared no impact of SARS-CoV2 pandemic on the transplant timing and outcomes, and the sanitary policy was positively evaluated by the majority of centers. The emergency measures ensured that only a minority of the allo-HCT patients had been infected by SARS-CoV2; however, a mortality of 42.1% among the allo-HCT patients hospitalized for COVID-19 was recorded. This survey gives us the information that the GITMO Group reacted positively to the pandemic. Thanks to the emergency strategies, the Italian allo-HCT activity continued safely, showing only a minor deflection and offering the same probability of cure to the transplanted patients.
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spelling pubmed-80541302021-04-19 Changes in Stem Cell Transplant activity and procedures during SARS-CoV2 pandemic in Italy: an Italian Bone Marrow Transplant Group (GITMO) nationwide analysis (TransCOVID-19 Survey) Russo, Domenico Polverelli, Nicola Malagola, Michele Farina, Mirko Leoni, Alessandro Bernardi, Simona Mammoliti, Sonia Sacchi, Nicoletta Martino, Massimo Ciceri, Fabio Bone Marrow Transplant Correspondence The Transplant Centers belonging to Gruppo Italiano per il Trapianto di Midollo Osseo (GITMO) conducted a survey with the aim of evaluating the effect of SARS-CoV2 pandemic on the allogeneic transplant activity in Italy. The pandemic period from 1/3/2020 to 31/7/2020 was compared with the same period in 2019. Overall, in 2020 there was a 2.4% reduction in the number of allo-HCT cases compared to 2019. Interestingly, this deflection did not affect the acute leukemia cases (+5.7% in 2020). The use of peripheral blood-derived stem cells (+10.7%) and cryopreservation (97.4% of the centers) was highly adopted in 2020. Despite the sanitary emergency, almost all of the surveyed centers declared no impact of SARS-CoV2 pandemic on the transplant timing and outcomes, and the sanitary policy was positively evaluated by the majority of centers. The emergency measures ensured that only a minority of the allo-HCT patients had been infected by SARS-CoV2; however, a mortality of 42.1% among the allo-HCT patients hospitalized for COVID-19 was recorded. This survey gives us the information that the GITMO Group reacted positively to the pandemic. Thanks to the emergency strategies, the Italian allo-HCT activity continued safely, showing only a minor deflection and offering the same probability of cure to the transplanted patients. Nature Publishing Group UK 2021-04-19 2021 /pmc/articles/PMC8054130/ /pubmed/33875810 http://dx.doi.org/10.1038/s41409-021-01287-w Text en © The Author(s), under exclusive licence to Springer Nature Limited 2021 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Correspondence
Russo, Domenico
Polverelli, Nicola
Malagola, Michele
Farina, Mirko
Leoni, Alessandro
Bernardi, Simona
Mammoliti, Sonia
Sacchi, Nicoletta
Martino, Massimo
Ciceri, Fabio
Changes in Stem Cell Transplant activity and procedures during SARS-CoV2 pandemic in Italy: an Italian Bone Marrow Transplant Group (GITMO) nationwide analysis (TransCOVID-19 Survey)
title Changes in Stem Cell Transplant activity and procedures during SARS-CoV2 pandemic in Italy: an Italian Bone Marrow Transplant Group (GITMO) nationwide analysis (TransCOVID-19 Survey)
title_full Changes in Stem Cell Transplant activity and procedures during SARS-CoV2 pandemic in Italy: an Italian Bone Marrow Transplant Group (GITMO) nationwide analysis (TransCOVID-19 Survey)
title_fullStr Changes in Stem Cell Transplant activity and procedures during SARS-CoV2 pandemic in Italy: an Italian Bone Marrow Transplant Group (GITMO) nationwide analysis (TransCOVID-19 Survey)
title_full_unstemmed Changes in Stem Cell Transplant activity and procedures during SARS-CoV2 pandemic in Italy: an Italian Bone Marrow Transplant Group (GITMO) nationwide analysis (TransCOVID-19 Survey)
title_short Changes in Stem Cell Transplant activity and procedures during SARS-CoV2 pandemic in Italy: an Italian Bone Marrow Transplant Group (GITMO) nationwide analysis (TransCOVID-19 Survey)
title_sort changes in stem cell transplant activity and procedures during sars-cov2 pandemic in italy: an italian bone marrow transplant group (gitmo) nationwide analysis (transcovid-19 survey)
topic Correspondence
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8054130/
https://www.ncbi.nlm.nih.gov/pubmed/33875810
http://dx.doi.org/10.1038/s41409-021-01287-w
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