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Streptococcus dysgalactiae-related intrathecal baclofen therapy infection: how to avoid withdrawal?

Intrathecal baclofen therapy is commonly used for neurologically spastic patients. One of the major complications is hardware infection, which generally requires urgent removal of the pump and the intrathecal catheter, with the risk of severe baclofen withdrawal. We have recently been facing this si...

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Detalles Bibliográficos
Autores principales: De Larminat, V., Zayet, S., Klopfenstein, T., Idelcadi, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8054186/
https://www.ncbi.nlm.nih.gov/pubmed/33898045
http://dx.doi.org/10.1016/j.nmni.2021.100875
Descripción
Sumario:Intrathecal baclofen therapy is commonly used for neurologically spastic patients. One of the major complications is hardware infection, which generally requires urgent removal of the pump and the intrathecal catheter, with the risk of severe baclofen withdrawal. We have recently been facing this situation and propose another solution with adapted antibiotic therapy, removal with immediate replacement of the intrathecal catheter, initially connected to an implanted port to continue baclofen administration. A new pump was secondarily implanted, after successful treatment of acute bacterial meningitis due to Streptococcus dysgalactiae.