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Choline restores respiration in Psd1-deficient yeast by replenishing mitochondrial phosphatidylethanolamine

Phosphatidylethanolamine (PE) is essential for mitochondrial respiration in yeast, Saccharomyces cerevisiae, whereas the most abundant mitochondrial phospholipid, phosphatidylcholine (PC), is largely dispensable. Surprisingly, choline (Cho), which is a biosynthetic precursor of PC, has been shown to...

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Detalles Bibliográficos
Autores principales:	Iadarola, Donna M., Joshi, Alaumy, Caldwell, Cameron B., Gohil, Vishal M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8054189/ https://www.ncbi.nlm.nih.gov/pubmed/33722607 http://dx.doi.org/10.1016/j.jbc.2021.100539

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