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HLA Ligand Atlas: a benign reference of HLA-presented peptides to improve T-cell-based cancer immunotherapy
BACKGROUND: The human leucocyte antigen (HLA) complex controls adaptive immunity by presenting defined fractions of the intracellular and extracellular protein content to immune cells. Understanding the benign HLA ligand repertoire is a prerequisite to define safe T-cell-based immunotherapies agains...
Autores principales: | Marcu, Ana, Bichmann, Leon, Kuchenbecker, Leon, Kowalewski, Daniel Johannes, Freudenmann, Lena Katharina, Backert, Linus, Mühlenbruch, Lena, Szolek, András, Lübke, Maren, Wagner, Philipp, Engler, Tobias, Matovina, Sabine, Wang, Jian, Hauri-Hohl, Mathias, Martin, Roland, Kapolou, Konstantina, Walz, Juliane Sarah, Velz, Julia, Moch, Holger, Regli, Luca, Silginer, Manuela, Weller, Michael, Löffler, Markus W., Erhard, Florian, Schlosser, Andreas, Kohlbacher, Oliver, Stevanović, Stefan, Rammensee, Hans-Georg, Neidert, Marian Christoph |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8054196/ https://www.ncbi.nlm.nih.gov/pubmed/33858848 http://dx.doi.org/10.1136/jitc-2020-002071 |
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