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Pneumatosis Intestinalis Due to COVID-19 Infection in Kidney Transplant Recipient: A Case Report
BACKGROUND: Pneumatosis intestinalis (PI) is a rare condition usually occurring among adults who have undergone solid organ transplant and are taking steroid therapy. The coronavirus disease 2019 (COVID-19) virus uses angiotensin-converting enzyme 2 in gastrointestinal epithelium as a receptor for e...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8054270/ https://www.ncbi.nlm.nih.gov/pubmed/33678444 http://dx.doi.org/10.1016/j.transproceed.2021.01.039 |
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author | Łaski, D. Biernat, K. Kaska, Ł. |
author_facet | Łaski, D. Biernat, K. Kaska, Ł. |
author_sort | Łaski, D. |
collection | PubMed |
description | BACKGROUND: Pneumatosis intestinalis (PI) is a rare condition usually occurring among adults who have undergone solid organ transplant and are taking steroid therapy. The coronavirus disease 2019 (COVID-19) virus uses angiotensin-converting enzyme 2 in gastrointestinal epithelium as a receptor for entry process. Due to the steroid intake, the COVID-19 virus is present in the patient's gastrointestinal tract for extended period of time. It may therefore increase the possibility of PI in such patients. It is usually asymptomatic, with a clinical spectrum ranging from indolent to life-threatening. Unfortunately, there are no algorithms concerning diagnosis and treatment of PI. AIM OF STUDY: The aim of this study is to highlight the problem of PI induced by COVID-19, especially in high-risk groups such as solid organs recipients. CONCLUSION: On the basis of the presented case of a severe course of COVID-19–induced PI, we conclude that laparotomy with bowel resection can be a feasible and a safe option for treatment. |
format | Online Article Text |
id | pubmed-8054270 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Elsevier Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-80542702021-04-19 Pneumatosis Intestinalis Due to COVID-19 Infection in Kidney Transplant Recipient: A Case Report Łaski, D. Biernat, K. Kaska, Ł. Transplant Proc Article BACKGROUND: Pneumatosis intestinalis (PI) is a rare condition usually occurring among adults who have undergone solid organ transplant and are taking steroid therapy. The coronavirus disease 2019 (COVID-19) virus uses angiotensin-converting enzyme 2 in gastrointestinal epithelium as a receptor for entry process. Due to the steroid intake, the COVID-19 virus is present in the patient's gastrointestinal tract for extended period of time. It may therefore increase the possibility of PI in such patients. It is usually asymptomatic, with a clinical spectrum ranging from indolent to life-threatening. Unfortunately, there are no algorithms concerning diagnosis and treatment of PI. AIM OF STUDY: The aim of this study is to highlight the problem of PI induced by COVID-19, especially in high-risk groups such as solid organs recipients. CONCLUSION: On the basis of the presented case of a severe course of COVID-19–induced PI, we conclude that laparotomy with bowel resection can be a feasible and a safe option for treatment. Elsevier Inc. 2021-05 2021-02-02 /pmc/articles/PMC8054270/ /pubmed/33678444 http://dx.doi.org/10.1016/j.transproceed.2021.01.039 Text en © 2021 Elsevier Inc. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
spellingShingle | Article Łaski, D. Biernat, K. Kaska, Ł. Pneumatosis Intestinalis Due to COVID-19 Infection in Kidney Transplant Recipient: A Case Report |
title | Pneumatosis Intestinalis Due to COVID-19 Infection in Kidney Transplant Recipient: A Case Report |
title_full | Pneumatosis Intestinalis Due to COVID-19 Infection in Kidney Transplant Recipient: A Case Report |
title_fullStr | Pneumatosis Intestinalis Due to COVID-19 Infection in Kidney Transplant Recipient: A Case Report |
title_full_unstemmed | Pneumatosis Intestinalis Due to COVID-19 Infection in Kidney Transplant Recipient: A Case Report |
title_short | Pneumatosis Intestinalis Due to COVID-19 Infection in Kidney Transplant Recipient: A Case Report |
title_sort | pneumatosis intestinalis due to covid-19 infection in kidney transplant recipient: a case report |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8054270/ https://www.ncbi.nlm.nih.gov/pubmed/33678444 http://dx.doi.org/10.1016/j.transproceed.2021.01.039 |
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