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Pneumatosis Intestinalis Due to COVID-19 Infection in Kidney Transplant Recipient: A Case Report

BACKGROUND: Pneumatosis intestinalis (PI) is a rare condition usually occurring among adults who have undergone solid organ transplant and are taking steroid therapy. The coronavirus disease 2019 (COVID-19) virus uses angiotensin-converting enzyme 2 in gastrointestinal epithelium as a receptor for e...

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Detalles Bibliográficos
Autores principales: Łaski, D., Biernat, K., Kaska, Ł.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8054270/
https://www.ncbi.nlm.nih.gov/pubmed/33678444
http://dx.doi.org/10.1016/j.transproceed.2021.01.039
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author Łaski, D.
Biernat, K.
Kaska, Ł.
author_facet Łaski, D.
Biernat, K.
Kaska, Ł.
author_sort Łaski, D.
collection PubMed
description BACKGROUND: Pneumatosis intestinalis (PI) is a rare condition usually occurring among adults who have undergone solid organ transplant and are taking steroid therapy. The coronavirus disease 2019 (COVID-19) virus uses angiotensin-converting enzyme 2 in gastrointestinal epithelium as a receptor for entry process. Due to the steroid intake, the COVID-19 virus is present in the patient's gastrointestinal tract for extended period of time. It may therefore increase the possibility of PI in such patients. It is usually asymptomatic, with a clinical spectrum ranging from indolent to life-threatening. Unfortunately, there are no algorithms concerning diagnosis and treatment of PI. AIM OF STUDY: The aim of this study is to highlight the problem of PI induced by COVID-19, especially in high-risk groups such as solid organs recipients. CONCLUSION: On the basis of the presented case of a severe course of COVID-19–induced PI, we conclude that laparotomy with bowel resection can be a feasible and a safe option for treatment.
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spelling pubmed-80542702021-04-19 Pneumatosis Intestinalis Due to COVID-19 Infection in Kidney Transplant Recipient: A Case Report Łaski, D. Biernat, K. Kaska, Ł. Transplant Proc Article BACKGROUND: Pneumatosis intestinalis (PI) is a rare condition usually occurring among adults who have undergone solid organ transplant and are taking steroid therapy. The coronavirus disease 2019 (COVID-19) virus uses angiotensin-converting enzyme 2 in gastrointestinal epithelium as a receptor for entry process. Due to the steroid intake, the COVID-19 virus is present in the patient's gastrointestinal tract for extended period of time. It may therefore increase the possibility of PI in such patients. It is usually asymptomatic, with a clinical spectrum ranging from indolent to life-threatening. Unfortunately, there are no algorithms concerning diagnosis and treatment of PI. AIM OF STUDY: The aim of this study is to highlight the problem of PI induced by COVID-19, especially in high-risk groups such as solid organs recipients. CONCLUSION: On the basis of the presented case of a severe course of COVID-19–induced PI, we conclude that laparotomy with bowel resection can be a feasible and a safe option for treatment. Elsevier Inc. 2021-05 2021-02-02 /pmc/articles/PMC8054270/ /pubmed/33678444 http://dx.doi.org/10.1016/j.transproceed.2021.01.039 Text en © 2021 Elsevier Inc. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Łaski, D.
Biernat, K.
Kaska, Ł.
Pneumatosis Intestinalis Due to COVID-19 Infection in Kidney Transplant Recipient: A Case Report
title Pneumatosis Intestinalis Due to COVID-19 Infection in Kidney Transplant Recipient: A Case Report
title_full Pneumatosis Intestinalis Due to COVID-19 Infection in Kidney Transplant Recipient: A Case Report
title_fullStr Pneumatosis Intestinalis Due to COVID-19 Infection in Kidney Transplant Recipient: A Case Report
title_full_unstemmed Pneumatosis Intestinalis Due to COVID-19 Infection in Kidney Transplant Recipient: A Case Report
title_short Pneumatosis Intestinalis Due to COVID-19 Infection in Kidney Transplant Recipient: A Case Report
title_sort pneumatosis intestinalis due to covid-19 infection in kidney transplant recipient: a case report
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8054270/
https://www.ncbi.nlm.nih.gov/pubmed/33678444
http://dx.doi.org/10.1016/j.transproceed.2021.01.039
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AT kaskał pneumatosisintestinalisduetocovid19infectioninkidneytransplantrecipientacasereport