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Mitochondrial protein CMPK2 regulates IFN alpha-enhanced foam cell formation, potentially contributing to premature atherosclerosis in SLE

BACKGROUND: Premature atherosclerosis occurs in patients with SLE; however, the mechanisms remain unclear. Both mitochondrial machinery and proinflammatory cytokine interferon alpha (IFN-α) potentially contribute to atherogenic processes in SLE. Here, we explore the roles of the mitochondrial protei...

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Detalles Bibliográficos
Autores principales:	Lai, Jenn-Haung, Hung, Li-Feng, Huang, Chuan-Yueh, Wu, De-Wei, Wu, Chien-Hsiang, Ho, Ling-Jun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8054390/ https://www.ncbi.nlm.nih.gov/pubmed/33874983 http://dx.doi.org/10.1186/s13075-021-02470-6

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