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PTEN loss correlates with T cell exclusion across human cancers

BACKGROUND: Recent evidences had shown that loss in phosphatase and tensin homolog deleted on chromosome 10 (PTEN) was associated with immunotherapy resistance, which may be attributed to the non-T-cell-inflamed tumor microenvironment. The impact of PTEN loss on tumor microenvironment, especially re...

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Detalles Bibliográficos
Autores principales:	Lin, Ziying, Huang, Lixia, Li, Shao Li, Gu, Jincui, Cui, Xiaoxian, Zhou, Yanbin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8054401/ https://www.ncbi.nlm.nih.gov/pubmed/33874915 http://dx.doi.org/10.1186/s12885-021-08114-x

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