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Cyproheptadine, an epigenetic modifier, exhibits anti-tumor activity by reversing the epigenetic silencing of IRF6 in urothelial carcinoma
BACKGROUND: Urothelial carcinoma (UC) is the second most common malignancy of the urinary system with high rate of recurrence, UC patients therefore needed to be treated with surgery followed by chemotherapy. Development of novel therapeutics with minimal side-effect is an urgent issue. Our previous...
Autores principales: | Jou, Yeong-Chin, Lin, Guan-Ling, Lin, Hon-Yi, Huang, Wan-Hong, Chuang, Yu-Ming, Lin, Ru-Inn, Chen, Pie-Che, Wu, Shu-Fen, Shen, Cheng-Huang, Chan, Michael W. Y. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8054409/ https://www.ncbi.nlm.nih.gov/pubmed/33874979 http://dx.doi.org/10.1186/s12935-021-01925-9 |
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