SARS‑CoV-2 RBD219-N1C1: A yeast-expressed SARS-CoV-2 recombinant receptor-binding domain candidate vaccine stimulates virus neutralizing antibodies and T-cell immunity in mice

There is an urgent need for an accessible and low-cost COVID-19 vaccine suitable for low- and middle-income countries. Here, we report on the development of a SARS-CoV-2 receptor-binding domain (RBD) protein, expressed at high levels in yeast (Pichia pastoris), as a suitable vaccine candidate agains...

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Detalles Bibliográficos
Autores principales: Pollet, Jeroen, Chen, Wen-Hsiang, Versteeg, Leroy, Keegan, Brian, Zhan, Bin, Wei, Junfei, Liu, Zhuyun, Lee, Jungsoon, Kundu, Rahki, Adhikari, Rakesh, Poveda, Cristina, Villar, Maria Jose, de Araujo Leao, Ana Carolina, Altieri Rivera, Joanne, Momin, Zoha, Gillespie, Portia M., Kimata, Jason T., Strych, Ulrich, Hotez, Peter J., Bottazzi, Maria Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8054496/
https://www.ncbi.nlm.nih.gov/pubmed/33847226
http://dx.doi.org/10.1080/21645515.2021.1901545

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