Profiling SARS-CoV-2 mutation fingerprints that range from the viral pangenome to individual infection quasispecies

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BACKGROUND: The genome of SARS-CoV-2 is susceptible to mutations during viral replication due to the errors generated by RNA-dependent RNA polymerases. These mutations enable the SARS-CoV-2 to evolve into new strains. Viral quasispecies emerge from de novo mutations that occur in individual patients...

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Detalles Bibliográficos
Autores principales: Lau, Billy T., Pavlichin, Dmitri, Hooker, Anna C., Almeda, Alison, Shin, Giwon, Chen, Jiamin, Sahoo, Malaya K., Huang, Chun Hong, Pinsky, Benjamin A., Lee, Ho Joon, Ji, Hanlee P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8054698/
https://www.ncbi.nlm.nih.gov/pubmed/33875001
http://dx.doi.org/10.1186/s13073-021-00882-2
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