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Persistent Hypercoagulable State in COVID-19: A Case Series of COVID-19 Associated Pulmonary Embolism
Coronavirus disease 2019 (COVID-19) has swept through the world with millions of cases and hundreds of thousands of deaths. COVID-19-associated coagulopathy has been recognized as the major cause of morbidity and mortality. To the best of our knowledge, a majority of the cases of coagulopathy have b...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer - Medknow
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8054785/ https://www.ncbi.nlm.nih.gov/pubmed/33911452 http://dx.doi.org/10.4103/jgid.jgid_180_20 |
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author | Chan, Kok Hoe Lim, Su Lin Shaaban, Hamid Guron, Gunwant Slim, Jihad |
author_facet | Chan, Kok Hoe Lim, Su Lin Shaaban, Hamid Guron, Gunwant Slim, Jihad |
author_sort | Chan, Kok Hoe |
collection | PubMed |
description | Coronavirus disease 2019 (COVID-19) has swept through the world with millions of cases and hundreds of thousands of deaths. COVID-19-associated coagulopathy has been recognized as the major cause of morbidity and mortality. To the best of our knowledge, a majority of the cases of coagulopathy have been reported in patients with moderate-to-severe COVID-19 and limited to observations during the recovery/postcytokine storm state. Herein, we report a case series of two patients with COVID-19 who developed pulmonary embolism in the late phase of the disease. This raised the hypothesis that the risk of hypercoagulability in patients with COVID-19 can persist until the recovery phase, which would warrant a follow-up with D-dimer and fibrinogen trending, as well as postdischarge thromboprophylaxis for at least 2 weeks during the recovery phase. |
format | Online Article Text |
id | pubmed-8054785 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Wolters Kluwer - Medknow |
record_format | MEDLINE/PubMed |
spelling | pubmed-80547852021-04-27 Persistent Hypercoagulable State in COVID-19: A Case Series of COVID-19 Associated Pulmonary Embolism Chan, Kok Hoe Lim, Su Lin Shaaban, Hamid Guron, Gunwant Slim, Jihad J Glob Infect Dis Case Series Coronavirus disease 2019 (COVID-19) has swept through the world with millions of cases and hundreds of thousands of deaths. COVID-19-associated coagulopathy has been recognized as the major cause of morbidity and mortality. To the best of our knowledge, a majority of the cases of coagulopathy have been reported in patients with moderate-to-severe COVID-19 and limited to observations during the recovery/postcytokine storm state. Herein, we report a case series of two patients with COVID-19 who developed pulmonary embolism in the late phase of the disease. This raised the hypothesis that the risk of hypercoagulability in patients with COVID-19 can persist until the recovery phase, which would warrant a follow-up with D-dimer and fibrinogen trending, as well as postdischarge thromboprophylaxis for at least 2 weeks during the recovery phase. Wolters Kluwer - Medknow 2021-01-29 /pmc/articles/PMC8054785/ /pubmed/33911452 http://dx.doi.org/10.4103/jgid.jgid_180_20 Text en Copyright: © 2021 Journal of Global Infectious Diseases https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms. |
spellingShingle | Case Series Chan, Kok Hoe Lim, Su Lin Shaaban, Hamid Guron, Gunwant Slim, Jihad Persistent Hypercoagulable State in COVID-19: A Case Series of COVID-19 Associated Pulmonary Embolism |
title | Persistent Hypercoagulable State in COVID-19: A Case Series of COVID-19 Associated Pulmonary Embolism |
title_full | Persistent Hypercoagulable State in COVID-19: A Case Series of COVID-19 Associated Pulmonary Embolism |
title_fullStr | Persistent Hypercoagulable State in COVID-19: A Case Series of COVID-19 Associated Pulmonary Embolism |
title_full_unstemmed | Persistent Hypercoagulable State in COVID-19: A Case Series of COVID-19 Associated Pulmonary Embolism |
title_short | Persistent Hypercoagulable State in COVID-19: A Case Series of COVID-19 Associated Pulmonary Embolism |
title_sort | persistent hypercoagulable state in covid-19: a case series of covid-19 associated pulmonary embolism |
topic | Case Series |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8054785/ https://www.ncbi.nlm.nih.gov/pubmed/33911452 http://dx.doi.org/10.4103/jgid.jgid_180_20 |
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