Cargando…

Effect of Teriflunomide on Cells From Patients With Human T-cell Lymphotropic Virus Type 1–Associated Neurologic Disease

OBJECTIVE: To test the hypothesis that teriflunomide can reduce ex vivo spontaneous proliferation of peripheral blood mononuclear cells (PBMCs) from patients with human T-cell lymphotropic virus type 1 (HTLV-1)–associated myelopathy/tropical spastic paraparesis (HAM/TSP). METHODS: PBMCs from patient...

Descripción completa

Detalles Bibliográficos
Autores principales:	Enose-Akahata, Yoshimi, Ngouth, Nyater, Ohayon, Joan, Mandel, Matt, Chavin, Jeffrey, Turner, Timothy J., Jacobson, Steven
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams & Wilkins 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8054963/ https://www.ncbi.nlm.nih.gov/pubmed/33837058 http://dx.doi.org/10.1212/NXI.0000000000000986

Ejemplares similares

Immunopathogenic CSF TCR repertoire signatures in virus-associated neurologic disease
por: Nozuma, Satoshi, et al.
Publicado: (2021)

Immunophenotypic characterization of CSF B cells in virus-associated neuroinflammatory diseases
por: Enose-Akahata, Yoshimi, et al.
Publicado: (2018)

Development of neurologic diseases in a patient with primate T lymphotropic virus type 1 (PTLV-1)
por: Enose-Akahata, Yoshimi, et al.
Publicado: (2016)

Clinical trial of raltegravir, an integrase inhibitor, in HAM/TSP
por: Enose‐Akahata, Yoshimi, et al.
Publicado: (2021)

Development of HTLV-1 associated myelopathy/tropical spastic paraparesis in a patient with simian T-lymphotropic virus type 1-like infection.
por: Enose-Akahata, Yoshimi, et al.
Publicado: (2015)

Clinical trial of a humanized anti‐IL‐2/IL‐15 receptor β chain in HAM/TSP
por: Enose‐Akahata, Yoshimi, et al.
Publicado: (2019)

Immunophenotyping of cerebrospinal fluid cells in virus-associated neurologic diseases
por: Enose-Akahata, Yoshimi, et al.
Publicado: (2015)

HTLV-1 epigenetic modification of the FoxP3 TSDR in HAM/TSP decreases the functional proliferative suppression of Tregs
por: Anderson, Monique R, et al.
Publicado: (2014)

Viral Immune signatures from cerebrospinal fluid extracellular vesicles and particles in HAM and other chronic neurological diseases
por: Pleet, Michelle L., et al.
Publicado: (2023)

High Expression of CD244 and SAP Regulated CD8(+) T Cell Responses of Patients with HTLV-I Associated Neurologic Disease
por: Enose-Akahata, Yoshimi, et al.
Publicado: (2009)

T cell receptor repertoire analysis in HTLV-1-associated diseases
por: Clauze, Annaliese, et al.
Publicado: (2022)

Immunovirological markers in HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP)
por: Enose-Akahata, Yoshimi, et al.
Publicado: (2019)

Minocycline modulates antigen-specific CTL activity through inactivation of mononuclear phagocytes in patients with HTLV-I associated neurologic disease
por: Enose-Akahata, Yoshimi, et al.
Publicado: (2012)

Role of HTLV-1 Tax and HBZ in the Pathogenesis of HAM/TSP
por: Enose-Akahata, Yoshimi, et al.
Publicado: (2017)

Clinical trial of a humanized monoclonal anti-IL15Rβ (CD122), in HTLV-1 associated myelopathy/ tropical spastic paraparesis (HAM/TSP)
por: Massoud, Raya, et al.
Publicado: (2014)

The repertoire of CSF antiviral antibodies in patients with neuroinflammatory diseases
por: Enose-Akahata, Yoshimi, et al.
Publicado: (2023)

Digital droplet PCR for precise quantification of human T-lymphotropic virus 1 proviral loads
por: Brunetto, Giovanna S, et al.
Publicado: (2014)

Correlation of increased CXCL13 with intrathecal humoral immune responses to HTLV-1 in CSF of patients with HAM/TSP
por: Enose-Akahata, Yoshimi, et al.
Publicado: (2014)

BNZ-gamma peptide, a potential therapeutic agent in HTLV-1 associated myelopathy
por: Massoud, Raya, et al.
Publicado: (2014)

Identification and tracking of HTLV-1–infected T cell clones in virus-associated neurologic disease
por: Nozuma, Satoshi, et al.
Publicado: (2023)

Vaccine Response in Patients With Multiple Sclerosis Receiving Teriflunomide
por: Tornatore, Carlo, et al.
Publicado: (2022)

Teriflunomide Inhibits JCPyV Infection and Spread in Glial Cells and Choroid Plexus Epithelial Cells
por: O’Hara, Bethany A., et al.
Publicado: (2021)

Viral antigens detectable in CSF exosomes from patients with retrovirus associated neurologic disease: functional role of exosomes
por: Anderson, Monique R., et al.
Publicado: (2018)

Digital droplet PCR (ddPCR) for the precise quantification of human T-lymphotropic virus 1 proviral loads in peripheral blood and cerebrospinal fluid of HAM/TSP patients and identification of viral mutations
por: Brunetto, Giovanna S., et al.
Publicado: (2014)

Comparison of qPCR with ddPCR for the Quantification of JC Polyomavirus in CSF from Patients with Progressive Multifocal Leukoencephalopathy
por: Ngouth, Nyater, et al.
Publicado: (2022)

Humoral immune response to HTLV-1 basic leucine zipper factor (HBZ) in HTLV-1-infected individuals
por: Enose-Akahata, Yoshimi, et al.
Publicado: (2013)

Humoral immune response to HTLV-1 basic leucine zipper factor (HBZ) in HTLV-1-infected individuals
por: Enose-Akahata, Yoshimi, et al.
Publicado: (2014)

Prior treatment status: impact on the efficacy and safety of teriflunomide in multiple sclerosis
por: Comi, Giancarlo, et al.
Publicado: (2020)

The Prevalence and Significance of HTLV-I/II Seroindeterminate Western Blot Patterns
por: Abrams, Anna, et al.
Publicado: (2011)

Neuroimmunology of Human T-Lymphotropic Virus Type 1-Associated Myelopathy/Tropical Spastic Paraparesis
por: Nozuma, Satoshi, et al.
Publicado: (2019)

Teriflunomide reduces relapse-related neurological sequelae, hospitalizations and steroid use
por: O’Connor, Paul W., et al.
Publicado: (2013)

Prevalence and influence of tuberculosis in the neurologic manifestations of the Human T cell lymphotropic virus type 1 (HTLV-1)
por: de Lourdes Bastos, Maria, et al.
Publicado: (2014)

Medical conditions, social and neurological patients of the T-lymphotropic virus humanities-HTLV I
por: Gaspar, GLC, et al.
Publicado: (2014)

Human T-Lymphotropic Virus Type 1 (HTLV-1) and Regulatory T Cells in HTLV-1-Associated Neuroinflammatory Disease
por: Araya, Natsumi, et al.
Publicado: (2011)

COVID‐19 in a human T‐cell lymphotropic virus type‐1 carrier
por: Enomoto, Takatoshi, et al.
Publicado: (2022)

Deep Phenotyping of Neurologic Postacute Sequelae of SARS-CoV-2 Infection
por: Mina, Yair, et al.
Publicado: (2023)

Barefoot Plantar Pressure Indicates Progressive Neurological Damage in Patients with Human T-Cell Lymphotropic Virus Type 1 Infection
por: Vasconcelos, Beatriz Helena B., et al.
Publicado: (2016)

Effectiveness and Tolerability of Colesevelam HCl for Accelerated Elimination of Teriflunomide in Healthy Participants
por: Lunven, Catherine, et al.
Publicado: (2017)

Teriflunomide treatment reduces B cells in patients with MS
por: Gandoglia, Ilaria, et al.
Publicado: (2017)

Quantitative differences in antibody responses between normal donors HAM/TSP patients, asymptomatic carriers, and ATL patients from Jamaica: can they be used to estimate risk of disease?
por: Akahata, Yoshimi, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_eh87tk6km7ai0rpicffllpckob