Integration in oncogenes plays only a minor role in determining the in vivo distribution of HIV integration sites before or during suppressive antiretroviral therapy

HIV persists during antiretroviral therapy (ART) as integrated proviruses in cells descended from a small fraction of the CD4+ T cells infected prior to the initiation of ART. To better understand what controls HIV persistence and the distribution of integration sites (IS), we compared about 15,000...

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Detalles Bibliográficos
Autores principales: Coffin, John M., Bale, Michael J., Wells, Daria, Guo, Shuang, Luke, Brian, Zerbato, Jennifer M., Sobolewski, Michele D., Sia, Twan, Shao, Wei, Wu, Xiaolin, Maldarelli, Frank, Kearney, Mary F., Mellors, John W., Hughes, Stephen H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8055010/
https://www.ncbi.nlm.nih.gov/pubmed/33826675
http://dx.doi.org/10.1371/journal.ppat.1009141

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